About   Help   FAQ
Slc5a4b Gene Detail
Summary
  • Symbol
    Slc5a4b
  • Name
    solute carrier family 5 (neutral amino acid transporters, system A), member 4b
  • Synonyms
    2010104G07Rik, pSGLT2, SAAT1, SGLT3b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890478
    NCBI Gene: 64454
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:75894452-75946852 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 38.68 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890478
 protein coding gene Chr10:75893328-75946852 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017376
 protein coding gene Chr10:76272252-76327560 (-)
A/J MGP_AJ_G0017353
 protein coding gene Chr10:73644995-73700146 (-)
AKR/J MGP_AKRJ_G0017314
 protein coding gene Chr10:75627417-75683779 (-)
BALB/cJ MGP_BALBcJ_G0017313
 protein coding gene Chr10:73845490-73901438 (-)
C3H/HeJ MGP_C3HHeJ_G0017137
 protein coding gene Chr10:75687413-75746990 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017771
 protein coding gene Chr10:78967893-79033564 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015461
 protein coding gene Chr10:70090113-70144842 (-)
CAST/EiJ MGP_CASTEiJ_G0016707
 protein coding gene Chr10:76002164-76060801 (-)
CBA/J MGP_CBAJ_G0017109
 protein coding gene Chr10:82057595-82124769 (-)
DBA/2J MGP_DBA2J_G0017214
 protein coding gene Chr10:72955487-73010586 (-)
FVB/NJ MGP_FVBNJ_G0017206
 protein coding gene Chr10:72112412-72165605 (-)
LP/J MGP_LPJ_G0017287
 protein coding gene Chr10:76783561-76844305 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017235
 protein coding gene Chr10:84131325-84201043 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017810
 protein coding gene Chr10:75670640-75733415 (-)
PWK/PhJ MGP_PWKPhJ_G0016491
 protein coding gene Chr10:72774554-72835957 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016274
 protein coding gene Chr10:74906924-74965920 (-)
WSB/EiJ MGP_WSBEiJ_G0016770
 protein coding gene Chr10:75651012-75710894 (-)



Homology
more
  • Human Ortholog
    SLC5A4, solute carrier family 5 member 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC5A4, solute carrier family 5 member 4
  • Synonyms
    DJ90G24.4, SAAT1, SGLT3
  • Links
    NCBI Gene ID: 6527
    neXtProt AC: NX_Q9NY91
    UniProt: Q9NY91

  • Chr Location
    22q12.3; chr22:32218464-32355063 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    13
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 64454 NCBI Gene Model | MGI Sequence Detail 52401 C57BL/6J ±  kb
transcript NM_023219 RefSeq | MGI Sequence Detail 2132 C57BL/6  
polypeptide Q91ZP4 UniProt | EBI | MGI Sequence Detail 660 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR038377 Sodium/glucose symporter superfamily
    IPR001734 Sodium/solute symporter
    IPR018212 Sodium/solute symporter, conserved site
Molecular
Reagents
less
  • All nucleic 16
    Genomic 2
    cDNA 13
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1913793
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:210441 Yamazaki Y, et al., Sodium-glucose transporter type 3-mediated neuroprotective effect of acetylcholine suppresses the development of cerebral ischemic neuronal damage. Neuroscience. 2014 Jun 6;269:134-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory