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Pcbp3 Gene Detail
Summary
  • Symbol
    Pcbp3
  • Name
    poly(rC) binding protein 3
  • Synonyms
    AlphaCP-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890470
    NCBI Gene: 59093
  • Gene Overview
    MyGene.info: PCBP3
Location & Maps
more
  • Sequence Map
    Chr10:76761857-76961887 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      200031 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband B5.1 - B5.3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PCBP3, poly(rC) binding protein 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PCBP3, poly(rC) binding protein 3
    Orthology source: HomoloGene
  • Synonyms
    ALPHA-CP3
  • Links
    NCBI Gene ID: 54039
    neXtProt AC: NX_P57721

  • Chr Location
    21q22.3; chr21:45849961-45942454 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 23233
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PCBP3
  • Gene Tree
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotype references
  • All Mutations and Alleles
    16
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Targeted
    5
  • Genomic Mutations
    4 involving Pcbp3
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035211 VEGA Gene Model | MGI Sequence Detail 200031 C57BL/6J ±  kb
transcript OTTMUST00000089693 VEGA | MGI Sequence Detail 2013 Not Applicable  
polypeptide OTTMUSP00000049044 VEGA | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1054 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000012337 poly(rC)-binding protein 3
  • InterPro Domains
    IPR004087 K Homology domain
    IPR004088 K Homology domain, type 1
Molecular
Reagents
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  • All nucleic 64
    cDNA 62
    Primer pair 2

    Microarray probesets 5
References
more
  • Summaries
    All 36
    Developmental Gene Expression 7
    Diseases 2
    Gene Ontology 4
    Phenotypes 20
  • Earliest
    J:63824 Makeyev AV, et al., Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins. Genomics. 2000 Aug 1;67(3):301-16
  • Latest
    J:185427 Kang DH, et al., Novel dual-binding function of a poly (C)-binding protein 3, transcriptional factor which binds the double-strand and single-stranded DNA sequence. Gene. 2012 Jun 10;501(1):33-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory