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Ear6
Gene Detail
 Symbol
Name
ID
Ear6
eosinophil-associated, ribonuclease A family, member 6
MGI:1890463
Feature Type protein coding gene
Genetic Map
Chromosome 14
26.70 cM, cytoband B-C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:51853699-51854643 bp, + strand
From VEGA annotation of GRCm38

  945 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40596  Vertebrate Homology Class
4 mouse

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Ear6

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ear6 interacts with 45 markers (Mir20a, Mir22, Mir34a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process RNA phosphodiester bond hydrolysis
Component cellular_component
Function endonuclease activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000036430 (Evidence)
Ensembl Gene ModelENSMUSG00000062148 (Evidence)
Entrez Gene93719 (Evidence)
UniGene221324
DoTSDT.101716383
Consensus CDS ProjectCCDS27045.1
International Mouse Knockout Project StatusEar6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036430 VEGA Gene Model | MGI Sequence Detail 945 C57BL/6J ±  kb
transcript OTTMUST00000093340 VEGA | MGI Sequence Detail 893 Not Applicable 
polypeptide OTTMUSP00000051750 VEGA | MGI Sequence Detail 155 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(109 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001427 Ribonuclease A
InterPro IPR023411 Ribonuclease A, active site
InterPro IPR023412 Ribonuclease A-domain
References (Earliest) J:69087 Cormier SA, et al., Mouse eosinophil-associated ribonucleases: a unique subfamily expressed during hematopoiesis. Mamm Genome. 2001 May;12(5):352-61
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(18)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory