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Slc15a2
Gene Detail
Symbol

Name
ID
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
MGI:1890457
Synonyms
8430408C16Rik, Pept2
Feature Type
protein coding gene
Genetic Map
Chromosome 16
25.97 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:36750178-36784962 bp, - strand
From VEGA annotation of GRCm38

  34785 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56912  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC15A2
Protein SuperFamily: peptide transport protein PEPT1
Gene Tree: Slc15a2

Human
homologs
SLC15A2, solute carrier family 15 (oligopeptide transporter), member 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6565
neXtProt AC: NX_Q16348

Human Synonyms: PEPT2

Human Chr (Location): 3q13.33; chr3:121894324-121944187 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous mutant mice have impairments of dipeptide transportion, however, show no gross defects.
 
Interactions
Slc15a2 interacts with 266 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process antibiotic transport, dipeptide transport, ...
Component extracellular exosome, integral component of plasma membrane, ...
Function antibiotic transporter activity, dipeptide transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (194)    Tissues (100)    Images (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 194
cDNA source data(53)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc15a2 ; ZFIN slc15a2    NEW 
Molecular
reagents
All nucleic(55) cDNA(53) Primer pair(2)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000035783 (Evidence)
Ensembl Gene Model ENSMUSG00000022899 (Evidence)
Entrez Gene 57738 (Evidence)
UniGene 281804
DFCI TC1670825, TC1715823, TC1586368, TC1580860
DoTS DT.40184156, DT.94264969, DT.486744
NIA Mouse Gene Index U037022
Consensus CDS Project CCDS28156.1, CCDS49842.1
International Mouse Phenotyping Consortium Status Slc15a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035783 VEGA Gene Model | MGI Sequence Detail 34785 C57BL/6J ±  kb
transcript OTTMUST00000091574 VEGA | MGI Sequence Detail 3993 Not Applicable 
polypeptide OTTMUSP00000050453 VEGA | MGI Sequence Detail 740 Not Applicable 

For the selected sequences
All sequences(90) RefSeq(9) UniProt(11)
Polymorphisms
SNPs within 2kb(330 from dbSNP Build 137)    SNPs within 2kb including multiple locations(332)
Protein-related
information
ResourceIDDescription
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR004768 Oligopeptide transporter
InterPro IPR000109 Proton-dependent oligopeptide transporter family
InterPro IPR018456 PTR2 family proton/oligopeptide symporter, conserved site
Protein Ontology PR:000014941 solute carrier family 15 member 2
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:214959 Lodato S, et al., Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014 Aug;17(8):1046-54
All references(41)
Other
accession IDs
MGI:1918747, MGI:2146702

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory