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Zfp110
Gene Detail
 Symbol
Name
ID
Zfp110
zinc finger protein 110
MGI:1890378
Synonyms 2900024E01Rik, NRIF, Nrif1
Feature Type protein coding gene
Genetic Map
Chromosome 7
7.66 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:12834761-12850577 bp, + strand
From VEGA annotation of GRCm38

  15817 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:129707  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Gene Tree: Zfp110

Human
homologs
Human Homolog ZNF274, zinc finger protein 274
NCBI Gene ID 10782
neXtProt AC  NX_Q96GC6
Human Synonyms  HFB101, ZF2, ZKSCAN19, ZSCAN51
Human Chr (Location)  19qter; chr19:58182989-58213562 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutants on a C57BL/6 background die at embryonic day 12. On a strain 129 background, mutants are viable and fertile, but males are more docile and testis weight is greatly reduced. On an F2 background, 20% of homozygous pups die neonatally.
 
Interactions
Zfp110 interacts with 127 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process apoptotic process, extrinsic apoptotic signaling pathway, ...
Component centrosome, cytoplasm, ...
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (78)    Tissues (57)    Images (4)
Theiler Stages: 2, 3, 4, 5, 15, 17, 21, 23, 27, 28
Assay TypeResults
RNA in situ 70
RT-PCR 8
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000022354 (Evidence)
Ensembl Gene ModelENSMUSG00000058638 (Evidence)
Entrez Gene65020 (Evidence)
DFCITC1576361, TC1622675
DoTSDT.527550, DT.94260821
NIA Mouse Gene IndexU042785
Consensus CDS ProjectCCDS20814.1
International Mouse Knockout Project StatusZfp110
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022354 VEGA Gene Model | MGI Sequence Detail 15817 C57BL/6J ±  kb
transcript OTTMUST00000053345 VEGA | MGI Sequence Detail 3591 Not Applicable 
polypeptide OTTMUSP00000025366 VEGA | MGI Sequence Detail 832 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(120 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001909 Krueppel-associated box
InterPro IPR008916 Retrovirus capsid, C-terminal
InterPro IPR003309 Transcription regulator SCAN
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
References (Earliest) J:66924 Casademunt E, et al., The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death. EMBO J. 1999 Nov 1;18(21):6050-61
(Latest) J:199694 Liang Y, et al., Structural analysis and dimerization profile of the SCAN domain of the pluripotency factor Zfp206. Nucleic Acids Res. 2012 Sep 1;40(17):8721-32
All references(44)
Other
accession IDs
MGI:1920172, MGI:2142379

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory