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Igf2bp3 Gene Detail
Summary
  • Symbol
    Igf2bp3
  • Name
    insulin-like growth factor 2 mRNA binding protein 3
  • Synonyms
    2610101N11Rik, IMP3, Koc13
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890359
    NCBI Gene: 140488
  • Gene Overview
    MyGene.info: IGF2BP3
Location & Maps
more
  • Sequence Map
    Chr6:49085223-49214957 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      129735 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 23.82 cM, cytoband B2.3
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    IGF2BP3, insulin like growth factor 2 mRNA binding protein 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IGF2BP3, insulin like growth factor 2 mRNA binding protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CT98, IMP3, IMP-3, KOC, KOC1, VICKZ3
  • Links
    NCBI Gene ID: 10643
    neXtProt AC: NX_O00425
    UniProt: O00425

  • Chr Location
    7p15.3; chr7:23310209-23470674 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    41
  • Tissues
    35
  • cDNA Data
    15
  • Literature Summary
    13
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057404 VEGA Gene Model | MGI Sequence Detail 129735 C57BL/6J ±  kb
transcript OTTMUST00000141214 VEGA | MGI Sequence Detail 4345 Not Applicable  
polypeptide OTTMUSP00000073832 VEGA | MGI Sequence Detail 579 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    557 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    Genomic 3
    cDNA 17
    Primer pair 1
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1919721, MGI:2141367, MGI:2141534, MGI:2141597
References
more
  • Summaries
    All 47
    Developmental Gene Expression 13
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:30335 Duh JL, et al., The Y-box motif mediates redox-dependent transcriptional activation in mouse cells. J Biol Chem. 1995 Dec 22;270(51):30499-507
  • Latest
    J:235757 Degrauwe N, et al., The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing. Cell Rep. 2016 May 24;15(8):1634-47
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/20/2017
MGI 6.10 		The Jackson Laboratory