About   Help   FAQ
Fxyd6
Gene Detail
Symbol

Name
ID
Fxyd6
FXYD domain-containing ion transport regulator 6
MGI:1890226
Synonyms
0610030I18Rik, Php
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:45370185-45396158 bp, + strand
From Ensembl annotation of GRCm38

  25974 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11090  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: FXYD domain-containing ion transport regulator
Gene Tree: Fxyd6

Human
homologs
Human Homolog FXYD6, FXYD domain containing ion transport regulator 6
NCBI Gene ID 53826
neXtProt AC  NX_Q9H0Q3
Human Chr (Location)  11q23.3; chr11:117836976-117877486 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(53) : Gene trapped(53)
 
Mice homozygous for a null gene trap insertion exhibit impaired learning/memory during trace aversive conditioning when compared with that of their wild-type littermates.
 
Interactions
Fxyd6 interacts with 127 markers (Mir10a, Mir10b, Mir17, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process ion transport, transport
Component integral component of membrane, membrane, ...
Function ion channel activity
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (85)    Tissues (24)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 85
cDNA source data(16)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(16)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000066705 (Evidence)
Entrez Gene59095 (Evidence)
DFCITC1608872, TC1575694, TC1587372, TC1647950
DoTSDT.40136954, DT.101403247, DT.496373
NIA Mouse Gene IndexU010414
Consensus CDS ProjectCCDS23133.1
International Mouse Knockout Project StatusFxyd6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066705 Ensembl Gene Model | MGI Sequence Detail 25974 C57BL/6J ±  kb
transcript ENSMUST00000085939 Ensembl | MGI Sequence Detail 1791 Not Applicable 
polypeptide ENSMUSP00000083101 Ensembl | MGI Sequence Detail 94 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(391 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000272 Ion-transport regulator, FXYD motif
Protein Ontology PR:000031781 FXYD domain-containing ion transport regulator 6
References
(Earliest) J:64123 Sweadner KJ, et al., The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression. Genomics. 2000 Aug 15;68(1):41-56
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(41)
Other
accession IDs
MGI:1913338

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory