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Fetub Gene Detail
Summary
  • Symbol
    Fetub
  • Name
    fetuin beta
  • Synonyms
    2310011O17Rik, D17980
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890221
    NCBI Gene: 59083
  • Gene Overview
    MyGene.info: FETUB
  • Alliance
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:22918382-22939768 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 13.76 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    94 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890221
protein coding gene Chr16:22918382-22939768 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022675
protein coding gene Chr16:20448610-20466660 (+)
A/J MGP_AJ_G0022636
protein coding gene Chr16:19458103-19477999 (+)
AKR/J MGP_AKRJ_G0022611
protein coding gene Chr16:20248620-20291766 (+)
BALB/cJ MGP_BALBcJ_G0022641
protein coding gene Chr16:19659267-19676556 (+)
C3H/HeJ MGP_C3HHeJ_G0022405
protein coding gene Chr16:20354075-20399082 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023091
protein coding gene Chr16:20900549-20910976 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020609
protein coding gene Chr16:20151780-20166720 (+)
CAST/EiJ MGP_CASTEiJ_G0021935
protein coding gene Chr16:20379615-20396403 (+)
CBA/J MGP_CBAJ_G0022377
protein coding gene Chr16:21733561-21784390 (+)
DBA/2J MGP_DBA2J_G0022509
protein coding gene Chr16:19439159-19454363 (+)
FVB/NJ MGP_FVBNJ_G0022485
protein coding gene Chr16:19408668-19430199 (+)
LP/J MGP_LPJ_G0022577
protein coding gene Chr16:20198492-20217351 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022504
protein coding gene Chr16:21304712-21320722 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023102
protein coding gene Chr16:20218760-20235189 (+)
PWK/PhJ MGP_PWKPhJ_G0021675
protein coding gene Chr16:19683242-19698444 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021505
protein coding gene Chr16:20008945-20023669 (+)
WSB/EiJ MGP_WSBEiJ_G0021978
protein coding gene Chr16:20187475-20202362 (+)



Homology
more
  • Human Ortholog
    FETUB, fetuin B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FETUB, fetuin B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    16G2, Gugu, IRL685
  • Links
    NCBI Gene ID: 26998
    neXtProt AC: NX_Q9UGM5
    UniProt: Q9UGM5

  • Chr Location
    3q27.3; chr3:186635828-186653008 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8660
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FETUB
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 2 genetic backgrounds
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit female infertility due to premature hardening of the zona pellucida.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 59083 NCBI Gene Model | MGI Sequence Detail 21387 C57BL/6J ±  kb
    transcript NM_021564 RefSeq | MGI Sequence Detail 1600 C57BL/6  
    polypeptide Q9QXC1 UniProt | EBI | MGI Sequence Detail 388 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 83
      cDNA 83

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1915165, MGI:2146393
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 2
    • Earliest
      J:64478 Olivier E, et al., Fetuin-B, a second member of the fetuin family in mammals. Biochem J. 2000 Sep 1;350 Pt 2:589-97
    • Latest
      J:196435 Dietzel E, et al., Fetuin-B, a liver-derived plasma protein is essential for fertilization. Dev Cell. 2013 Apr 15;25(1):106-12

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory