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Slc6a14 Gene Detail
Summary
  • Symbol
    Slc6a14
  • Name
    solute carrier family 6 (neurotransmitter transporter), member 14
  • Synonyms
    1110007A17Rik, 9030613J17Rik, ATB0plus, CATB0plus
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890216
    NCBI Gene: 56774
  • Gene Overview
    MyGene.info: SLC6A14
Location & Maps
more
  • Sequence Map
    ChrX:21714896-21742355 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      27460 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 16.78 cM, cytoband A2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC6A14, solute carrier family 6 member 14
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC6A14, solute carrier family 6 member 14
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BMIQ11
  • Links
    NCBI Gene ID: 11254
    neXtProt AC: NX_Q9UN76

  • Chr Location
    Xq23; chrX:116436579-116461458 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Targeted
    4
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017212 VEGA Gene Model | MGI Sequence Detail 27460 C57BL/6J ±  kb
transcript OTTMUST00000041681 VEGA | MGI Sequence Detail 3434 Not Applicable  
polypeptide OTTMUSP00000018719 VEGA | MGI Sequence Detail 638 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    16 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000015180 sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
  • InterPro Domains
    IPR000175 Sodium:neurotransmitter symporter
Molecular
Reagents
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  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
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MGI:1921088, MGI:1921782
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:64926 Sloan JL, et al., Cloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+). J Biol Chem. 1999 Aug 20;274(34):23740-5
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory