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Rnf25 Gene Detail
Summary
  • Symbol
    Rnf25
  • Name
    ring finger protein 25
  • Synonyms
    0610009H16Rik, AO7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890215
    NCBI Gene: 57751
  • Gene Overview
    MyGene.info: RNF25
Location & Maps
more
  • Sequence Map
    Chr1:74593748-74601397 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7650 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 38.54 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    RNF25, ring finger protein 25
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RNF25, ring finger protein 25
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AO7
  • Links
    NCBI Gene ID: 64320
    neXtProt AC: NX_Q96BH1

  • Chr Location
    2q35; chr2:218663864-218672058 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Rnf25
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021746 VEGA Gene Model | MGI Sequence Detail 7650 C57BL/6J ±  kb
transcript OTTMUST00000051604 VEGA | MGI Sequence Detail 1479 Not Applicable  
polypeptide OTTMUSP00000024323 VEGA | MGI Sequence Detail 456 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    44 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 5
Other
Accession IDs
less
MGI:1913312
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 17
  • Earliest
    J:64924 Lorick KL, et al., RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11364-9
  • Latest
    J:182258 Taher L, et al., Global gene expression analysis of murine limb development. PLoS One. 2011;6(12):e28358

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory