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Larp1 Gene Detail
Summary
  • Symbol
    Larp1
  • Name
    La ribonucleoprotein domain family, member 1
  • Synonyms
    1810024J12Rik, 3110040D16Rik, Larp, mKIAA0731
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890165
    NCBI Gene: 73158
  • Gene Overview
    MyGene.info: LARP1
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:58009064-58062034 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 35.55 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    282 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890165
protein coding gene Chr11:57973275-58062034 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018341
protein coding gene Chr11:57675434-57730846 (+)
A/J MGP_AJ_G0018311
protein coding gene Chr11:55490548-55543304 (+)
AKR/J MGP_AKRJ_G0018280
protein coding gene Chr11:57318103-57376604 (+)
BALB/cJ MGP_BALBcJ_G0018282
protein coding gene Chr11:55835264-55887831 (+)
C3H/HeJ MGP_C3HHeJ_G0018093
protein coding gene Chr11:57241264-57297177 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018733
protein coding gene Chr11:59436141-59494880 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016383
protein coding gene Chr11:52846088-52899208 (+)
CAST/EiJ MGP_CASTEiJ_G0017658
protein coding gene Chr11:57326219-57385021 (+)
CBA/J MGP_CBAJ_G0018068
protein coding gene Chr11:62193364-62249003 (+)
DBA/2J MGP_DBA2J_G0018177
protein coding gene Chr11:55142194-55195148 (+)
FVB/NJ MGP_FVBNJ_G0018168
protein coding gene Chr11:54839653-54893673 (+)
LP/J MGP_LPJ_G0018252
protein coding gene Chr11:58209022-58265397 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018194
protein coding gene Chr11:63317578-63374410 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018776
protein coding gene Chr11:57338470-57393620 (+)
PWK/PhJ MGP_PWKPhJ_G0017430
protein coding gene Chr11:55739781-55794498 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017225
protein coding gene Chr11:57231613-57291982 (+)
WSB/EiJ MGP_WSBEiJ_G0017705
protein coding gene Chr11:56989301-57046409 (+)



Homology
more
  • Human Ortholog
    LARP1, La ribonucleoprotein domain family member 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LARP1, La ribonucleoprotein domain family member 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LARP
  • Links
    NCBI Gene ID: 23367
    neXtProt AC: NX_Q6PKG0
    UniProt: Q6PKG0

  • Chr Location
    5q33.2; chr5:154682663-154817607 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9089
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LARP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037331 Ensembl Gene Model | MGI Sequence Detail 52971 C57BL/6J ±  kb
transcript ENSMUST00000071487 Ensembl | MGI Sequence Detail 6614 Not Applicable  
polypeptide ENSMUSP00000071421 Ensembl | MGI Sequence Detail 1072 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR006630 La-type HTH domain
    IPR006607 Protein of unknown function DM15
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916410, MGI:1920408
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory