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Larp1 Gene Detail
Summary
  • Symbol
    Larp1
  • Name
    La ribonucleoprotein domain family, member 1
  • Synonyms
    1810024J12Rik, 3110040D16Rik, Larp, mKIAA0731
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890165
    NCBI Gene: 73158
  • Gene Overview
    MyGene.info: LARP1
Location & Maps
more
  • Sequence Map
    Chr11:58009064-58062031 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      52968 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 35.55 cM, cytoband B2
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    LARP1, La ribonucleoprotein domain family member 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LARP1, La ribonucleoprotein domain family member 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    LARP
  • Links
    NCBI Gene ID: 23367
    neXtProt AC: NX_Q6PKG0

  • Chr Location
    5q33.2; chr5:154682663-154817607 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9089
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: LARP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    39
  • Chemically induced (other)
    1
  • Gene trapped
    36
  • Targeted
    2
  • Genomic Mutations
    1 involving Larp1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005720 VEGA Gene Model | MGI Sequence Detail 52968 C57BL/6J ±  kb
transcript OTTMUST00000012716 VEGA | MGI Sequence Detail 6614 Not Applicable  
polypeptide OTTMUSP00000005891 VEGA | MGI Sequence Detail 1072 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    282 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000009668 La-related protein 1
  • InterPro Domains
    IPR006607 Protein of unknown function DM15
    IPR006630 RNA-binding protein Lupus La
    IPR011991 Winged helix-turn-helix DNA-binding domain
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
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MGI:1916410, MGI:1920408
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:63224 Chauvet S, et al., dlarp, a new candidate Hox target in Drosophila whose orthologue in mouse is expressed at sites of epithelium/mesenchymal interactions. Dev Dyn. 2000 Jul;218(3):401-13
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory