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Stx8
Gene Detail
Symbol

Name
ID
Stx8
syntaxin 8
MGI:1890156
Synonyms
0610007H08Rik, 1110002H11Rik, 4930571E13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
41.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:67966193-68207148 bp, + strand
From VEGA annotation of GRCm38

  240956 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37973  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: STX8
Protein SuperFamily: syntaxin 8
Gene Tree: Stx8

Human
homologs
STX8, syntaxin 8
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 9482
neXtProt AC: NX_Q9UNK0

Human Synonyms: CARB

Human Chr (Location): 17p12; chr17:9250471-9575958 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(47) : Gene trapped(42) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Stx8 interacts with 229 markers (Mir7-1, Mir7-2, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process early endosome to late endosome transport, endosome to lysosome transport, ...
Component early endosome, endosome, ...
Function chloride channel inhibitor activity, SNAP receptor activity, ...
External Resources: FuncBase
Expression
cDNA source data(57)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase stx8 ; ZFIN stx8    NEW 
Molecular
reagents
All nucleic(59) cDNA(59)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000005939 (Evidence)
Ensembl Gene Model ENSMUSG00000020903 (Evidence)
Entrez Gene 55943 (Evidence)
UniGene 3973
Consensus CDS Project CCDS24863.1
International Mouse Phenotyping Consortium Status Stx8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005939 VEGA Gene Model | MGI Sequence Detail 240956 C57BL/6J ±  kb
transcript OTTMUST00000013226 VEGA | MGI Sequence Detail 4394 Not Applicable 
polypeptide OTTMUSP00000006134 VEGA | MGI Sequence Detail 236 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(1180 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000727 Target SNARE coiled-coil homology domain
Protein Ontology PR:000015800 syntaxin-8
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:218388 Golebiewska EM, et al., Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability. J Biol Chem. 2015 Jan 16;290(3):1536-45
All references(38)
Other
accession IDs
MGI:1915004, MGI:1915791, MGI:1925545

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory