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Stx8
Gene Detail
 Symbol
Name
ID
Stx8
syntaxin 8
MGI:1890156
Synonyms 0610007H08Rik, 1110002H11Rik, 4930571E13Rik
Feature Type protein coding gene
Genetic Map
Chromosome 11
41.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:67966193-68207148 bp, + strand
From VEGA annotation of GRCm38

  240956 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37973  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: syntaxin 8
Gene Tree: Stx8

Human
homologs
Human Homolog STX8, syntaxin 8
NCBI Gene ID 9482
neXtProt AC  NX_Q9UNK0
Human Synonyms  CARB
Human Chr (Location)  17p12; chr17:9250471-9575958 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(47) : Gene trapped(42) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Stx8 interacts with 230 markers (Mir7-1, Mir7-2, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process endosome to lysosome transport, intracellular protein transport, ...
Component integral component of membrane, late endosome membrane, ...
Function SNAP receptor activity, SNARE binding, ...
External Resources: FuncBase
Expression
cDNA source data(57)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(59) cDNA(59)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000005939 (Evidence)
Ensembl Gene ModelENSMUSG00000020903 (Evidence)
Entrez Gene55943 (Evidence)
UniGene3973
Consensus CDS ProjectCCDS24863.1
International Mouse Knockout Project StatusStx8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005939 VEGA Gene Model | MGI Sequence Detail 240956 C57BL/6J ±  kb
transcript OTTMUST00000013226 VEGA | MGI Sequence Detail 4394 Not Applicable 
polypeptide OTTMUSP00000006134 VEGA | MGI Sequence Detail 236 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(1180 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000727 Target SNARE coiled-coil domain
Protein Ontology PR:000015800 syntaxin-8
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206800 Pirooz SD, et al., UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2716-21
All references(38)
Other
accession IDs
MGI:1915004, MGI:1915791, MGI:1925545

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory