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Plxnc1
Gene Detail
 Symbol
Name
ID
Plxnc1
plexin C1
MGI:1890127
Synonyms 2510048K12Rik, CD232, vespr
Feature Type protein coding gene
Genetic Map
Chromosome 10
49.09 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:94790866-94944578 bp, - strand
From VEGA annotation of GRCm38

  153713 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4211  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Plxnc1

Human
homologs
Human Homolog PLXNC1, plexin C1
NCBI Gene ID 10154
neXtProt AC  NX_O60486
Human Synonyms  CD232, PLXN-C1, VESPR
Human Chr (Location)  12q23.3; chr12:94148723-94307675 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit abnormal neuron morphology and migration.
 
Interactions
Plxnc1 interacts with 454 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process multicellular organismal development, signal transduction
Component integral component of membrane, intracellular, ...
Function receptor activity
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (284)    Tissues (194)    Images (34)
Theiler Stages: 2, 3, 4, 5, 16, 17, 19, 20, 21, 22, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 276
RT-PCR 8
cDNA source data(82)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(86) cDNA(84) Primer pair(2)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000042667 (Evidence)
Ensembl Gene ModelENSMUSG00000074785 (Evidence)
Entrez Gene54712 (Evidence)
UniGene256712
DFCITC1597538, TC1614049, TC1729875
DoTSDT.40171122, DT.55256077, DT.87055220, DT.94135538
NIA Mouse Gene IndexU032153
Consensus CDS ProjectCCDS48676.1
International Mouse Knockout Project StatusPlxnc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042667 VEGA Gene Model | MGI Sequence Detail 153713 C57BL/6J ±  kb
transcript OTTMUST00000112367 VEGA | MGI Sequence Detail 7045 Not Applicable 
polypeptide OTTMUSP00000063082 VEGA | MGI Sequence Detail 1574 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(4) UniProt(4)
Polymorphisms SNPs within 2kb(1010 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002909 Cell surface receptor IPT/TIG
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR002165 Plexin
InterPro IPR013548 Plexin, cytoplasmic RasGAP domain
InterPro IPR016201 Plexin-like fold
InterPro IPR008936 Rho GTPase activation protein
InterPro IPR001627 Semaphorin/CD100 antigen
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000001910 plexin-C1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:180764 Kang S, et al., Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via alphavbeta1 integrin. J Immunol. 2012 Feb 1;188(3):1108-16
All references(49)
Other
accession IDs
MGI:1921458, MGI:2143873

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory