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Plxnc1
Gene Detail
Symbol

Name
ID
Plxnc1
plexin C1
MGI:1890127
Synonyms
2510048K12Rik, CD232, vespr
Feature Type
protein coding gene
Genetic Map
Chromosome 10
49.09 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:94790866-94944578 bp, - strand
From VEGA annotation of GRCm38

  153713 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4211  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PLXNC1
Gene Tree: Plxnc1

Human
homologs
PLXNC1, plexin C1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10154
neXtProt AC: NX_O60486

Human Synonyms: CD232, PLXN-C1, VESPR

Human Chr (Location): 12q23.3; chr12:94148723-94307675 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit abnormal neuron morphology and migration.
 
Interactions
Plxnc1 interacts with 453 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process signal transduction
Component integral component of membrane, membrane
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (284)    Tissues (194)    Images (34)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 276
RT-PCR 8
cDNA source data(82)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase plxnc1    NEW 
Molecular
reagents
All nucleic(86) cDNA(84) Primer pair(2)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000042667 (Evidence)
Ensembl Gene Model ENSMUSG00000074785 (Evidence)
Entrez Gene 54712 (Evidence)
UniGene 256712
DFCI TC1729875, TC1614049, TC1597538
DoTS DT.40171122, DT.87055220, DT.55256077, DT.94135538
NIA Mouse Gene Index U032153
Consensus CDS Project CCDS48676.1
International Mouse Phenotyping Consortium Status Plxnc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042667 VEGA Gene Model | MGI Sequence Detail 153713 C57BL/6J ±  kb
transcript OTTMUST00000112367 VEGA | MGI Sequence Detail 7045 Not Applicable 
polypeptide OTTMUSP00000063082 VEGA | MGI Sequence Detail 1574 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(1010 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002909 Cell surface receptor IPT/TIG
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR002165 Plexin
InterPro IPR013548 Plexin, cytoplasmic RasGAP domain
InterPro IPR016201 Plexin-like fold
InterPro IPR008936 Rho GTPase activation protein
InterPro IPR001627 Semaphorin/CD100 antigen
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000001910 plexin-C1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:221786 Parkash J, et al., Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence. Nat Commun. 2015;6:6385
All references(49)
Other
accession IDs
MGI:1921458, MGI:2143873

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory