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Pidd1 Gene Detail
Summary
  • Symbol
    Pidd1
  • Name
    p53 induced death domain protein 1
  • Synonyms
    1200011D09Rik, Lrdd, Pidd
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889507
    NCBI Gene: 57913
  • Gene Overview
    MyGene.info: PIDD1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:141438113-141444025 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 86.79 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    58 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889507
protein coding gene Chr7:141438113-141445744 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033230
protein coding gene Chr7:146626757-146632669 (-)
A/J MGP_AJ_G0033212
protein coding gene Chr7:142432022-142437934 (-)
AKR/J MGP_AKRJ_G0033144
protein coding gene Chr7:146382193-146388105 (-)
BALB/cJ MGP_BALBcJ_G0033213
protein coding gene Chr7:142177209-142183104 (-)
C3H/HeJ MGP_C3HHeJ_G0032927
protein coding gene Chr7:146122400-146128312 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033724
protein coding gene Chr7:151978117-151984062 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030697
protein coding gene Chr7:143644132-143650001 (-)
CAST/EiJ MGP_CASTEiJ_G0032257
protein coding gene Chr7:138434384-138440287 (-)
CBA/J MGP_CBAJ_G0032899
protein coding gene Chr7:157142452-157148407 (-)
DBA/2J MGP_DBA2J_G0033051
protein coding gene Chr7:140380423-140386355 (-)
FVB/NJ MGP_FVBNJ_G0033004
protein coding gene Chr7:140295026-140300938 (-)
LP/J MGP_LPJ_G0033146
protein coding gene Chr7:148122790-148128685 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033037
protein coding gene Chr7:157773313-157779258 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033744
protein coding gene Chr7:145340721-145346676 (-)
PWK/PhJ MGP_PWKPhJ_G0031961
protein coding gene Chr7:133664592-133670523 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031808
protein coding gene Chr7:132177626-132183522 (-)
WSB/EiJ MGP_WSBEiJ_G0032368
protein coding gene Chr7:146291299-146298450 (-)



Homology
more
  • Human Ortholog
    PIDD1, p53-induced death domain protein 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    PIDD1, p53-induced death domain protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LRDD, PIDD
  • Links
    NCBI Gene ID: 55367
    neXtProt AC: NX_Q9HB75
    UniProt: Q9HB75

  • Chr Location
    11p15.5; chr11:799179-809504 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11220
    1 human;1 mouse;2 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PIDD1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Mice homozygous for a null allele were viable and did not show fertility problems, gender bias, other overt phenotype, or any gross abnormalities in histological assessment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025507 Ensembl Gene Model | MGI Sequence Detail 5913 C57BL/6J ±  kb
transcript ENSMUST00000026580 Ensembl | MGI Sequence Detail 3357 Not Applicable  
polypeptide ENSMUSP00000026580 Ensembl | MGI Sequence Detail 915 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    Genomic 1
    cDNA 39

    Microarray probesets 4
Other
Accession IDs
less
MGI:1918981, MGI:2142154
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 14
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:246097 Ando K, et al., NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus. J Cell Biol. 2017 Jun 05;216(6):1795-1810

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory