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B3gnt2
Gene Detail
Symbol

Name
ID
B3gnt2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
MGI:1889505
Synonyms
B3Galt6, B3gnt1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
14.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:22834747-22860961 bp, - strand
From VEGA annotation of GRCm38

  26215 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4797  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: B3GNT2
Gene Tree: B3gnt2

Human
homologs
B3GNT2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10678
neXtProt AC: NX_Q9NY97

Human Synonyms: B3GNT, B3GNT1, B3GN-T2, B3GNT-2, BETA3GNT, BGnT-2, BGNT2

Human Chr (Location): 2p15; chr2:62196127-62224731 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a gene trap allele show severe axon guidance errors and specific loss of olfactory sensory neurons and glomeruli. Homozygotes for another gene trap allele show hyperactive lymphocytes and macrophages. Homozygotes for a reporter allele display behavioral despair and reduced anxiety.
 
Interactions
B3gnt2 interacts with 233 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (205)    Tissues (152)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
In situ reporter (knock in) 58
Northern blot 16
RT-PCR 37
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase b3gnt2    NEW 
Molecular
reagents
All nucleic(15) cDNA(13) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000005266 (Evidence)
Ensembl Gene Model ENSMUSG00000051650 (Evidence)
Entrez Gene 53625 (Evidence)
DFCI TC1575950
EC 2.4.1.149
Consensus CDS Project CCDS24471.1
International Mouse Phenotyping Consortium Status B3gnt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005266 VEGA Gene Model | MGI Sequence Detail 26215 C57BL/6J ±  kb
transcript OTTMUST00000011735 VEGA | MGI Sequence Detail 3057 Not Applicable 
polypeptide OTTMUSP00000005434 VEGA | MGI Sequence Detail 397 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(4) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(89 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002659 Glycosyl transferase, family 31
Protein Ontology PR:000004592 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
References
(Earliest) J:62502 Zhou D, et al., A beta-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to beta-1,3-galactosyltransferases. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):406-11
(Latest) J:203671 Henion TR, et al., beta3GnT2 null mice exhibit defective accessory olfactory bulb innervation. Mol Cell Neurosci. 2013 Jan;52:73-86
All references(36)
Other
accession IDs
MGI:1890585, MGI:2143981, MGI:2143995, MGI:2144521

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory