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B3gnt2
Gene Detail
Symbol

Name
ID
B3gnt2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
MGI:1889505
Synonyms
B3Galt6, B3gnt1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
14.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:22834747-22860961 bp, - strand
From VEGA annotation of GRCm38

  26215 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4797  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: B3gnt2

Human
homologs
Human Homolog B3GNT2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
NCBI Gene ID 10678
neXtProt AC  NX_Q9NY97
Human Synonyms  B3GNT, B3GNT1, B3GN-T2, B3GNT-2, BETA3GNT, BGnT-2, BGNT2
Human Chr (Location)  2p15; chr2:62196127-62224731 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a gene trap allele show severe axon guidance errors and specific loss of olfactory sensory neurons and glomeruli. Homozygotes for another gene trap allele show hyperactive lymphocytes and macrophages. Homozygotes for a reporter allele display behavioral despair and reduced anxiety.
 
Interactions
B3gnt2 interacts with 233 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (205)    Tissues (152)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
In situ reporter (knock in) 58
Northern blot 16
RT-PCR 37
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(13) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000005266 (Evidence)
Ensembl Gene ModelENSMUSG00000051650 (Evidence)
Entrez Gene53625 (Evidence)
DFCITC1575950
EC2.4.1.-
Consensus CDS ProjectCCDS24471.1
International Mouse Knockout Project StatusB3gnt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005266 VEGA Gene Model | MGI Sequence Detail 26215 C57BL/6J ±  kb
transcript OTTMUST00000011735 VEGA | MGI Sequence Detail 3057 Not Applicable 
polypeptide OTTMUSP00000005434 VEGA | MGI Sequence Detail 397 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(4) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(89 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002659 Glycosyl transferase, family 31
Protein Ontology PR:000004592 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
References
(Earliest) J:62502 Zhou D, et al., A beta-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to beta-1,3-galactosyltransferases. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):406-11
(Latest) J:203671 Henion TR, et al., beta3GnT2 null mice exhibit defective accessory olfactory bulb innervation. Mol Cell Neurosci. 2013 Jan;52:73-86
All references(38)
Other
accession IDs
MGI:1890585, MGI:2143981, MGI:2143995, MGI:2144521

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory