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Ap1s2
Gene Detail
 Symbol
Name
ID
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
MGI:1889383
Synonyms 1500012A13Rik, EST1
Feature Type protein coding gene
Genetic Map
Chromosome X
75.97 cM, cytoband F5
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
ChrX:163909017-163933666 bp, + strand
From VEGA annotation of GRCm38

  24650 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2908  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: adaptor protein complex, sigma subunit
Gene Tree: Ap1s2

Human
homologs
Human Homolog AP1S2, adaptor-related protein complex 1, sigma 2 subunit
NCBI Gene ID 8905
neXtProt AC  NX_P56377
Human Synonyms  MGC:1902, MRX59, MRXS21, MRXS5, MRXSF, PGS, SIGMA1B
Human Chr (Location)  Xp22.2; chrX:15825806-15855014 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human AP1S2
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(4) Targeted(4)
Incidental mutations (data from APF )
Interactions
Ap1s2 interacts with 336 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process intracellular protein transport, protein transport, ...
Component coated pit, cytoplasmic vesicle, ...
Function protein transporter activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (6)    Tissues (2)    Images (3)
Theiler Stages: 23
Assay TypeResults
RNA in situ 6
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000019515 (Evidence)
Ensembl Gene ModelENSMUSG00000031367 (Evidence)
Entrez Gene108012 (Evidence)
DFCITC1575758, TC1589124, TC1609636, TC1706981, TC1759267
DoTSDT.101287884, DT.486222
NIA Mouse Gene IndexU020380
Consensus CDS ProjectCCDS30514.1, CCDS72465.1, CCDS72466.1
International Mouse Knockout Project StatusAp1s2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019515 VEGA Gene Model | MGI Sequence Detail 24650 C57BL/6J ±  kb
transcript OTTMUST00000046603 VEGA | MGI Sequence Detail 2226 Not Applicable 
polypeptide OTTMUSP00000021045 VEGA | MGI Sequence Detail 160 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(9) UniProt(5)
Polymorphisms RFLP(1) : SNPs within 2kb(3 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016635 Adaptor protein complex, sigma subunit
InterPro IPR022775 AP complex, mu/sigma subunit
InterPro IPR000804 Clathrin adaptor complex, small chain
InterPro IPR011012 Longin-like domain
Protein Ontology PR:000004097 AP-1 complex subunit sigma-2
References (Earliest) J:63696 Blair HJ, et al., Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and 253949) from the human X chromosome short arm with respect to evolutionary breakpoints on the mouse X chromosome. Mamm Genome. 2000 Aug;11(8):710-2
(Latest) J:193641 Nakano Y, et al., A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966
All references(36)
Other
accession IDs
MGI:1916210, MGI:2147933

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory