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Zfp318
Gene Detail
 Symbol
Name
ID
Zfp318
zinc finger protein 318
MGI:1889348
Synonyms 2610034E08Rik, D530032D06Rik, TZF
Feature Type protein coding gene
Genetic Map
Chromosome 17
22.90 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:46383731-46420920 bp, + strand
From VEGA annotation of GRCm38

  37190 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22808  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Zfp318

Human
homologs
Human Homolog ZNF318, zinc finger protein 318
NCBI Gene ID 24149
neXtProt AC  NX_Q5VUA4
Human Synonyms  TZF, ZFP318
Human Chr (Location)  6p21.1; chr6:43336070-43369443 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Chemically induced (ENU)(1) Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced allele exhibit reduced male fertility and altered IgM and IgD levels. While null mutants displayed normal level of circulating B cells with decreased IgD and increased IgM levels.
 
Interactions
Zfp318 interacts with 256 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process meiotic nuclear division, regulation of transcription, DNA-templated, ...
Component nucleus
Function metal ion binding, nucleic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (64)    Tissues (62)    Images (5)
Theiler Stages: 2, 3, 4, 5, 17, 18, 21, 23, 27, 28
Assay TypeResults
RNA in situ 56
RT-PCR 8
cDNA source data(67)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(68) cDNA(67) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000023200 (Evidence)
Ensembl Gene ModelENSMUSG00000015597 (Evidence)
Entrez Gene57908 (Evidence)
UniGene439916
DFCITC1581152, TC1589437, TC1589669, TC1604354, TC1657173, TC1746868
DoTSDT.483928, DT.91331721, DT.94332556, DT.97398679, DT.99855791
NIA Mouse Gene IndexU018037
Consensus CDS ProjectCCDS28826.2, CCDS28827.2
International Mouse Knockout Project StatusZfp318
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023200 VEGA Gene Model | MGI Sequence Detail 37190 C57BL/6J ±  kb
transcript OTTMUST00000056128 VEGA | MGI Sequence Detail 7850 Not Applicable 
polypeptide OTTMUSP00000026937 VEGA | MGI Sequence Detail 2237 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(5) UniProt(6)
Polymorphisms SNPs within 2kb(69 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR003604 Zinc finger, U1-type
Protein Ontology PR:000017821 zinc finger protein 318
References (Earliest) J:63318 Inoue A, et al., The transcript for a novel protein with a zinc finger motif is expressed at specific stages of mouse spermatogenesis. Biochem Biophys Res Commun. 2000 Jul 5;273(2):398-403
(Latest) J:207375 Enders A, et al., Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4513-8
All references(37)
Other
accession IDs
MGI:1916488, MGI:1925838

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory