Cbln3
Gene Detail

Symbol Name ID

Cbln3 cerebellin 3 precursor protein MGI:1889286

Feature Type

protein coding gene

Genetic Map

Chromosome 14

28.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr14:55878920-55884256 bp, - strand From NCBI annotation of GRCm38   5337 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:56861  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Cbln3

Human homologs

Human Homolog		CBLN3, cerebellin 3 precursor
NCBI Gene ID		643866
neXtProt AC		NX_Q6UW01
Human Synonyms		PRO1486
Human Chr (Location)		14q12; chr14:24895738-24898731 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(4) Gene trapped(1)
 

Mice homozygous for a knock-out allele are viable, fertile and behaviorally normal with no apparent defects in cerebellar foliation and lamination or Purkinje cell morphology.

 

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	biological_process
Component	cell junction, extracellular region, ...
Function	protein binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (41)    Tissues (27)    Images (13)
Theiler Stages: 19, 23, 28

Assay Type	Results
RNA in situ	41

cDNA source data(7)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(8) cDNA(7) Primer pair(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000040380 (Evidence)
Entrez Gene	56410 (Evidence)
UniGene	97163
DFCI	TC1584486, TC1596833, TC1610263
DoTS	DT.55174749, DT.55203631
NIA Mouse Gene Index	U035592
Consensus CDS Project	CCDS27133.1
International Mouse Knockout Project Status	Cbln3

Sequences

Length	Strain/Species
genomic	56410	NCBI Gene Model | MGI Sequence Detail	5337	C57BL/6J
transcript	NM_019820	RefSeq | MGI Sequence Detail	4723	C57BL/6
polypeptide	Q9JHG0	UniProt | EBI | MGI Sequence Detail	197	Not Applicable

All sequences(22) RefSeq(2) UniProt(2)

Polymorphisms

PCR(1) : SNPs(16 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001073	Complement C1q protein
InterPro	IPR008983	Tumour necrosis factor-like
Protein Ontology	PR:000005076	cerebellin-3

Graphical View of Protein Domain Structure

References

(Earliest) J:64199 Pang Z, et al., Cbln3, a novel member of the precerebellin family that binds specifically to cbln1. J Neurosci. 2000 Sep 1;20(17):6333-9
(Latest) J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All references(29)