About   Help   FAQ
Gipc2 Gene Detail
Summary
  • Symbol
    Gipc2
  • Name
    GIPC PDZ domain containing family, member 2
  • Synonyms
    2200002N01Rik, Semcap2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889209
    NCBI Gene: 54120
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:151799476-151871537 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 76.97 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    380 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889209
 protein coding gene Chr3:151799170-151871867 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027986
 protein coding gene Chr3:155932739-156007649 (-)
A/J MGP_AJ_G0027945
 protein coding gene Chr3:150283772-150358190 (-)
AKR/J MGP_AKRJ_G0027911
 protein coding gene Chr3:154236988-154316681 (-)
BALB/cJ MGP_BALBcJ_G0027957
 protein coding gene Chr3:150121781-150195973 (-)
C3H/HeJ MGP_C3HHeJ_G0027687
 protein coding gene Chr3:154682320-154760002 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028400
 protein coding gene Chr3:161076937-161159957 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025738
 protein coding gene Chr3:145121470-145194495 (-)
CAST/EiJ MGP_CASTEiJ_G0027140
 protein coding gene Chr3:154753133-154832115 (-)
CBA/J MGP_CBAJ_G0027662
 protein coding gene Chr3:166843808-166947763 (-)
DBA/2J MGP_DBA2J_G0027802
 protein coding gene Chr3:149390980-149465084 (-)
FVB/NJ MGP_FVBNJ_G0027769
 protein coding gene Chr3:146766831-146842724 (-)
LP/J MGP_LPJ_G0027913
 protein coding gene Chr3:157305090-157386716 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027802
 protein coding gene Chr3:175394641-175474212 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028459
 protein coding gene Chr3:153932173-154010123 (-)
PWK/PhJ MGP_PWKPhJ_G0026863
 protein coding gene Chr3:149272138-149348513 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026691
 protein coding gene Chr3:152086465-152168632 (-)
WSB/EiJ MGP_WSBEiJ_G0027220
 protein coding gene Chr3:154940481-155020340 (-)



Homology
more
  • Human Ortholog
    GIPC2, GIPC PDZ domain containing family member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GIPC2, GIPC PDZ domain containing family member 2
  • Synonyms
    SEMCAP2, SEMCAP-2
  • Links
    NCBI Gene ID: 54810
    neXtProt AC: NX_Q8TF65
    UniProt: Q8TF65

  • Chr Location
    1p31.1; chr1:77979542-78138444 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    757
  • Tissues
    21
  • cDNA Data
    36
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54120 NCBI Gene Model | MGI Sequence Detail 72062 C57BL/6J ±  kb
transcript NM_016867 RefSeq | MGI Sequence Detail 1286 Not Specified  
polypeptide Q9Z2H7 UniProt | EBI | MGI Sequence Detail 314 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 41
    cDNA 40
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913531, MGI:2139885
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:64422 Wang LH, et al., A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF. J Biol Chem. 1999 May 14;274(20):14137-46
  • Latest
    J:228590 La Torre A, et al., The GIPC1-Akt1 Pathway Is Required for the Specification of the Eye Field in Mouse Embryonic Stem Cells. Stem Cells. 2015 Sep;33(9):2674-85
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory