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Gipc2 Gene Detail
Summary
  • Symbol
    Gipc2
  • Name
    GIPC PDZ domain containing family, member 2
  • Synonyms
    2200002N01Rik, Semcap2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889209
    NCBI Gene: 54120
  • Gene Overview
    MyGene.info: GIPC2
Location & Maps
more
  • Sequence Map
    Chr3:152093533-152166230 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      72698 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 76.97 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    GIPC2, GIPC PDZ domain containing family member 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    GIPC2, GIPC PDZ domain containing family member 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SEMCAP2, SEMCAP-2
  • Links
    NCBI Gene ID: 54810
    neXtProt AC: NX_Q8TF65

  • Chr Location
    1p31.1; chr1:78024370-78138449 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031664 VEGA Gene Model | MGI Sequence Detail 72698 C57BL/6J ±  kb
transcript OTTMUST00000078449 VEGA | MGI Sequence Detail 1596 Not Applicable  
polypeptide OTTMUSP00000041709 VEGA | MGI Sequence Detail 314 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    380 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031654 PDZ domain-containing protein GIPC2
  • InterPro Domains
    IPR001478 PDZ domain
    IPR017379 Uncharacterised conserved protein UCP038083, PDZ
Molecular
Reagents
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  • All nucleic 40
    cDNA 39
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGI:1913531, MGI:2139885
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:64422 Wang LH, et al., A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF. J Biol Chem. 1999 May 14;274(20):14137-46
  • Latest
    J:228590 La Torre A, et al., The GIPC1-Akt1 Pathway Is Required for the Specification of the Eye Field in Mouse Embryonic Stem Cells. Stem Cells. 2015 Sep;33(9):2674-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory