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Cd200r1
Gene Detail
Symbol

Name
ID
Cd200r1
CD200 receptor 1
MGI:1889024
Synonyms
CD200R, Mox2r, OX2R
Feature Type
protein coding gene
Genetic Map
Chromosome 16
29.08 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:44765736-44794978 bp, + strand
From VEGA annotation of GRCm38

  29243 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10957  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog; 2 chicken; 5 western clawed frog

HCOP human homology predictions: CD200R1, CD200R1L
Gene Tree: Cd200r1

Human
homologs
CD200R1, CD200 receptor 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 131450
neXtProt AC: NX_Q8TD46

Human Synonyms: CD200R, HCRTR2, MOX2R, OX2R

Human Chr (Location): 3q13.2; chr3:112921057-112975122 (-)  GRCh38.p2

  1 More Homolog(s):
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a disruption of this gene display abnormal sleep patterns including fragmented vigilance states and diminished duration of wakefulness. Mice homozygous for a different knock-out allele exhibit protection from HSV-1 encephalitis.
 
Phenotype Images(2)
Interactions
Cd200r1 interacts with 59 markers (Mir1a-1, Mir1a-2, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Component external side of plasma membrane, integral component of membrane, ...
Function protein binding, receptor activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (67)    Tissues (32)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 67
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100485346    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000014978 (Evidence)
Ensembl Gene Model ENSMUSG00000022667 (Evidence)
Entrez Gene 57781 (Evidence)
UniGene 416152
DFCI TC1575356, TC1622412, TC1589785
NIA Mouse Gene Index U017167
PDB 4BFG, 4BFI
Consensus CDS Project CCDS28189.1
International Mouse Phenotyping Consortium Status Cd200r1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014978 VEGA Gene Model | MGI Sequence Detail 29243 C57BL/6J ±  kb
transcript OTTMUST00000035557 VEGA | MGI Sequence Detail 1892 Not Applicable 
polypeptide OTTMUSP00000015932 VEGA | MGI Sequence Detail 326 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(175 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013162 CD80-like, immunoglobulin C2-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000005161 cell surface glycoprotein CD200 receptor 1
References
(Earliest) J:64171 Wright GJ, et al., Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function. Immunity. 2000 Aug;13(2):233-42
(Latest) J:207783 Horie S, et al., CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization. Sci Rep. 2013;3:3072
All references(44)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory