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Cd200r1
Gene Detail
 Symbol
Name
ID
Cd200r1
CD200 receptor 1
MGI:1889024
Synonyms CD200R, Mox2r, OX2R
Feature Type protein coding gene
Genetic Map
Chromosome 16
29.08 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:44765736-44794978 bp, + strand
From VEGA annotation of GRCm38

  29243 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10957  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog; 2 chicken; 5 western clawed frog

Gene Tree: Cd200r1

Human
homologs
Human Homolog CD200R1, CD200 receptor 1
NCBI Gene ID 131450
neXtProt AC  NX_Q8TD46
Human Synonyms  CD200R, HCRTR2, MOX2R, OX2R
Human Chr (Location)  3q13.2; chr3:112922685-112975122 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a disruption of this gene display abnormal sleep patterns including fragmented vigilance states and diminished duration of wakefulness. Mice homozygous for a different knock-out allele exhibit protection from HSV-1 encephalitis.
 
Phenotype Images(2)
Interactions
Cd200r1 interacts with 59 markers (Mir1a-1, Mir1a-2, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Component external side of plasma membrane, integral component of membrane, ...
Function protein binding, receptor activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (67)    Tissues (32)    Images (32)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 67
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000014978 (Evidence)
Ensembl Gene ModelENSMUSG00000022667 (Evidence)
Entrez Gene57781 (Evidence)
UniGene416152
DFCITC1575356, TC1589785, TC1622412
NIA Mouse Gene IndexU017167
PDB4BFG, 4BFI
Consensus CDS ProjectCCDS28189.1
International Mouse Knockout Project StatusCd200r1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014978 VEGA Gene Model | MGI Sequence Detail 29243 C57BL/6J ±  kb
transcript OTTMUST00000035557 VEGA | MGI Sequence Detail 1892 Not Applicable 
polypeptide OTTMUSP00000015932 VEGA | MGI Sequence Detail 326 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(175 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013162 CD80-like, immunoglobulin C2-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000005161 cell surface glycoprotein CD200 receptor 1
References (Earliest) J:64171 Wright GJ, et al., Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function. Immunity. 2000 Aug;13(2):233-42
(Latest) J:207783 Horie S, et al., CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization. Sci Rep. 2013;3:3072
All references(45)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory