Sncb
Gene Detail

Symbol Name ID

Sncb synuclein, beta MGI:1889011

Synonyms

betaSYN

Feature Type

protein coding gene

Genetic Map

Chromosome 13

29.28 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr13:54758860-54766595 bp, - strand From VEGA annotation of GRCm38   7736 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2320  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: synuclein
Gene Tree: Sncb

Human homologs

Human Homolog		SNCB, synuclein, beta
NCBI Gene ID		6620
neXtProt AC		NX_Q16143
Human Chr (Location)		5q35; chr5:176047210-176057557 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SNCB

Alleles and phenotypes

All alleles(5) : Targeted(5)
 

Mice homozygous for disruptions in this gene display an essentially normal phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	dopamine metabolic process, negative regulation of neuron apoptotic process, ...
Component	axon terminus, cytoplasm, ...
Function	alpha-tubulin binding, beta-tubulin binding, ...

External Resources: FuncBase

Expression

Literature Summary: (7 records)
Data Summary: Results (44)    Tissues (38)    Images (23)
Theiler Stages: 19, 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	44

cDNA source data(24)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(26) cDNA(25) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000032668 (Evidence)
Ensembl Gene Model	ENSMUSG00000034891 (Evidence)
Entrez Gene	104069 (Evidence)
UniGene	200843
DFCI	TC1581008
DoTS	DT.486814
NIA Mouse Gene Index	U034804
Consensus CDS Project	CCDS36670.1
International Mouse Knockout Project Status	Sncb

Sequences

Length	Strain/Species
genomic	OTTMUSG00000032668	VEGA Gene Model | MGI Sequence Detail	7736	C57BL/6J
transcript	OTTMUST00000081255	VEGA | MGI Sequence Detail	1351	Not Applicable
polypeptide	OTTMUSP00000043434	VEGA | MGI Sequence Detail	133	Not Applicable

All sequences(27) RefSeq(2) UniProt(1)

Polymorphisms

PCR(1) : SNPs(40 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002461	Beta-synuclein
InterPro	IPR001058	Synuclein
Protein Ontology	PR:000015324	beta-synuclein

References

(Earliest) J:50153 Lavedan C, The synuclein family. Genome Res. 1998 Sep;8(9):871-80
(Latest) J:192811 Winner B, et al., Role of alpha-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus. J Neurosci. 2012 Nov 21;32(47):16906-16
All references(46)

Other accession IDs

MGI:2138328