About   Help   FAQ
Wdr4
Gene Detail
Symbol

Name
ID
Wdr4
WD repeat domain 4
MGI:1889002
Synonyms
D530049K22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
16.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:31494323-31519974 bp, - strand
From VEGA annotation of GRCm38

  25652 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32422  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Wdr4

Human
homologs
Human Homolog WDR4, WD repeat domain 4
NCBI Gene ID 10785
neXtProt AC  NX_P57081
Human Synonyms  TRM82, TRMT82
Human Chr (Location)  21q22.3; chr21:42843080-42879589 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(27) : Gene trapped(20) Targeted(7)
Genomic Mutations involving Wdr4 (4)
Incidental mutations (data from Mutagenetix , APF )
Alleles Annotated to Human Diseases(1)   
Interactions
Wdr4 interacts with 255 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process RNA (guanine-N7)-methylation, tRNA modification, ...
Component cytoplasm, nucleoplasm, ...
Function tRNA (guanine-N7-)-methyltransferase activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (132)    Tissues (66)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 98
RT-PCR 34
cDNA source data(70)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(73) cDNA(70) Primer pair(3)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000035223 (Evidence)
Ensembl Gene ModelENSMUSG00000024037 (Evidence)
Entrez Gene57773 (Evidence)
UniGene143771
DFCITC1598132, TC1642945, TC1577273
DoTSDT.488815, DT.101400426, DT.101400427
NIA Mouse Gene IndexU037651
Consensus CDS ProjectCCDS28606.2
International Mouse Knockout Project StatusWdr4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035223 VEGA Gene Model | MGI Sequence Detail 25652 C57BL/6J ±  kb
transcript OTTMUST00000089762 VEGA | MGI Sequence Detail 4153 Not Applicable 
polypeptide OTTMUSP00000049086 VEGA | MGI Sequence Detail 456 Not Applicable 

For the selected sequences
All sequences(99) RefSeq(24) UniProt(13)
Polymorphisms
SNPs within 2kb(111 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011044 Quinoprotein amine dehydrogenase, beta chain-like
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000017392 tRNA (guanine-N(7)-)-methyltransferase subunit WDR4
References
(Earliest) J:64125 Michaud J, et al., Isolation and characterization of a human chromosome 21q22.3 gene (WDR4) and its mouse homologue that code for a WD-repeat protein. Genomics. 2000 Aug 15;68(1):71-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGI:1926109, MGI:2146843, MGI:2146859

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory