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Api5 Gene Detail
Summary
  • Symbol
    Api5
  • Name
    apoptosis inhibitor 5
  • Synonyms
    AAC-11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1888993
    NCBI Gene: 11800
  • Gene Overview
    MyGene.info: API5
Location & Maps
more
  • Sequence Map
    Chr2:94411682-94438136 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26455 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 51.84 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    API5, apoptosis inhibitor 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    API5, apoptosis inhibitor 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    AAC11, AAC-11
  • Links
    NCBI Gene ID: 8539
    neXtProt AC: NX_Q9BZZ5

  • Chr Location
    11p11.2; chr11:43311955-43344530 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    23
  • Chemically induced (other)
    1
  • Gene trapped
    18
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Api5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014443 VEGA Gene Model | MGI Sequence Detail 26455 C57BL/6J ±  kb
transcript OTTMUST00000034264 VEGA | MGI Sequence Detail 3736 Not Applicable  
polypeptide OTTMUSP00000015342 VEGA | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    127 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 7
Other
Accession IDs
less
MGI:2138859
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:42738 Tewari M, et al., AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal. Cancer Res. 1997 Sep 15;57(18):4063-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory