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Sept6
Gene Detail
 Symbol
Name
ID
Sept6
septin 6
MGI:1888939
Synonyms 2810035H17Rik, C920001C06Rik
Feature Type protein coding gene
Genetic Map
Chromosome X
21.32 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:36911326-36991794 bp, - strand
From VEGA annotation of GRCm38

  80469 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:62617  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: septin
Gene Tree: Sept6

Human
homologs
Human Homolog SEPT6, septin 6
NCBI Gene ID 23157
neXtProt AC  NX_Q14141
Human Synonyms  SEP2, SEPT2
Human Chr (Location)  Xq24; chrX:119615724-119693370 (-)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(4) Gene trapped(1)
 
Homozygous females and hemizygous males harboring a knock-out mutation in this gene have a normal lifespan and display neither gross abnormalities, changes in cytokinesis, nor spontaneous malignancies including leukemia.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell cycle, cell division
Component axon terminus, chromosome, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (27)    Tissues (27)    Images (8)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 27
cDNA source data(19)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(19) cDNA(19)
Microarray probesets(12)
Other database
links
VEGA Gene ModelOTTMUSG00000017110 (Evidence)
Ensembl Gene ModelENSMUSG00000050379 (Evidence)
Entrez Gene56526 (Evidence)
NIA Mouse Gene IndexU069017, U211563
Consensus CDS ProjectCCDS30066.1, CCDS53051.1, CCDS57749.1
International Mouse Knockout Project StatusSept6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017110 VEGA Gene Model | MGI Sequence Detail 80469 C57BL/6J ±  kb
transcript OTTMUST00000041432 VEGA | MGI Sequence Detail 1845 Not Applicable 
polypeptide OTTMUSP00000018592 VEGA | MGI Sequence Detail 434 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(16) UniProt(3)
Polymorphisms SNPs within 2kb(123 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000038 Cell division protein GTP binding
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR016491 Septin
Protein Ontology PR:000014658 septin-6
References (Earliest) J:65529 Kinoshita A, et al., Differential localization of septins in the mouse brain. J Comp Neurol. 2000 Dec 11;428(2):223-39
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(41)
Other
accession IDs
MGI:1919926, MGI:2443232

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory