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Cyp2c44
Gene Detail
Symbol

Name
ID
Cyp2c44
cytochrome P450, family 2, subfamily c, polypeptide 44
MGI:1888897
Synonyms
MGC:25860, MGC:37835, MGC:37849
Feature Type
protein coding gene
Genetic Map
Chromosome 19
36.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:44005022-44029247 bp, - strand
From NCBI annotation of GRCm38

  24226 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:115563  Vertebrate Homology Class
1 mouse; 1 rat; 1 cattle; 1 dog; 2 chicken; 1 western clawed frog

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2c44

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(9) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced allele exhibit heterotaxy with cardiovascular anomalies, left lung and liver isomerism, and cleft palate.
 
Interactions
Cyp2c44 interacts with 89 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000025197 (Evidence)
Entrez Gene226143 (Evidence)
DFCITC1580533, TC1596045
DoTSDT.94125150, DT.94184557
NIA Mouse Gene IndexU039068
Consensus CDS ProjectCCDS29841.1
International Mouse Knockout Project StatusCyp2c44
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 226143 NCBI Gene Model | MGI Sequence Detail 24226 C57BL/6J ±  kb
transcript NM_001001446 RefSeq | MGI Sequence Detail 1964 C57BL/6 
polypeptide NP_001001446 RefSeq | MGI Sequence Detail 494 C57BL/6 

For the selected sequences
All sequences(37) RefSeq(4) UniProt(12)
Polymorphisms
SNPs within 2kb(114 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR020469 Cytochrome P450, CYP2 family
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008067 Cytochrome P450, E-class, group I, CYP2A-like
References
(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:204677 Zhang MZ, et al., Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney. Am J Physiol Renal Physiol. 2013 Dec 15;305(12):F1680-6
All references(31)
Other
accession IDs
MGI:2147705, MGI:2675854

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory