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Hist1h1t Gene Detail
Summary
  • Symbol
    Hist1h1t
  • Name
    histone cluster 1, H1t
  • Synonyms
    H1ft
  • Feature Type
    protein coding gene
  • IDs
    MGI:1888530
    NCBI Gene: 107970
  • Member of
    Hist1 cluster
  • Gene Overview
    MyGene.info: HIST1H1T
Location & Maps
more
  • Sequence Map
    Chr13:23695814-23696542 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      729 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.88 cM, cytoband A3.2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    HIST1H1T, histone cluster 1 H1 family member t
  • Vertebrate Orthologs
    34
  • Human Ortholog
    HIST1H1T, histone cluster 1 H1 family member t
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ221C16.2, H1.6, H1FT, H1t
  • Links
    NCBI Gene ID: 3010
    neXtProt AC: NX_P22492

  • Chr Location
    6p22.2; chr6:26107412-26108136 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 3 alleles in 4 genetic backgrounds
    7 phenotypes from multigenic genotypes
    13 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Hist1h1t
  • Incidental Mutations
Homozygous null mice develop normally and exhibit normal testicular morphology, spermatogenesis and fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000557 VEGA Gene Model | MGI Sequence Detail 729 C57BL/6J ±  kb
transcript OTTMUST00000001144 VEGA | MGI Sequence Detail 729 Not Applicable  
polypeptide OTTMUSP00000000525 VEGA | MGI Sequence Detail 209 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    67 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    Genomic 3
    cDNA 3
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 44
    Developmental Gene Expression 10
    Gene Ontology 8
    Phenotypes 13
  • Earliest
    J:15707 Drabent B, et al., Structure and expression of the mouse testicular H1 histone gene (H1t). Biochim Biophys Acta. 1993 Nov 16;1216(2):311-3
  • Latest
    J:229524 Robert T, et al., The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation. Science. 2016 Feb 26;351(6276):943-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory