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Xpo4 Gene Detail
Summary
  • Symbol
    Xpo4
  • Name
    exportin 4
  • Synonyms
    B430309A01Rik, mKIAA1721
  • Feature Type
    protein coding gene
  • IDs
    MGI:1888526
    NCBI Gene: 57258
  • Gene Overview
    MyGene.info: XPO4
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:57579755-57665512 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 30.11 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    320 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1888526
protein coding gene Chr14:57577521-57665512 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021409
protein coding gene Chr14:51778548-51873026 (-)
A/J MGP_AJ_G0021370
protein coding gene Chr14:50748689-50835369 (-)
AKR/J MGP_AKRJ_G0021345
protein coding gene Chr14:52533989-52621798 (-)
BALB/cJ MGP_BALBcJ_G0021373
protein coding gene Chr14:50694247-50781663 (-)
C3H/HeJ MGP_C3HHeJ_G0021152
protein coding gene Chr14:52180206-52268676 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021812
protein coding gene Chr14:54333051-54418213 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019352
protein coding gene Chr14:48826965-48911914 (-)
CAST/EiJ MGP_CASTEiJ_G0020670
protein coding gene Chr14:48515657-48602795 (-)
CBA/J MGP_CBAJ_G0021119
protein coding gene Chr14:55948744-56046099 (-)
DBA/2J MGP_DBA2J_G0021240
protein coding gene Chr14:50422253-50507691 (-)
FVB/NJ MGP_FVBNJ_G0021221
protein coding gene Chr14:49811965-49898637 (-)
LP/J MGP_LPJ_G0021315
protein coding gene Chr14:52821123-52910013 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021249
protein coding gene Chr14:55293726-55387518 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021836
protein coding gene Chr14:51682395-51773179 (-)
PWK/PhJ MGP_PWKPhJ_G0020413
protein coding gene Chr14:46963749-47049740 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020246
protein coding gene Chr14:47746723-47837902 (-)
WSB/EiJ MGP_WSBEiJ_G0020722
protein coding gene Chr14:51995007-52084675 (-)



Homology
more
  • Human Ortholog
    XPO4, exportin 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    XPO4, exportin 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    exp4
  • Links
    NCBI Gene ID: 64328
    neXtProt AC: NX_Q9C0E2
    UniProt: Q9C0E2

  • Chr Location
    13q12.11; chr13:20777329-20902774 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10733
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: XPO4
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Mice homozygous for a gene trapped allele appear phenotypically normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57258 NCBI Gene Model | MGI Sequence Detail 85758 C57BL/6J ±  kb
transcript NM_020506 RefSeq | MGI Sequence Detail 3456 Not Specified  
polypeptide Q9ESJ0 UniProt | EBI | MGI Sequence Detail 1151 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 69
    cDNA 69

    Microarray probesets 5
Other
Accession IDs
less
MGI:1925792
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:63907 Lipowsky G, et al., Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes. EMBO J. 2000 Aug 15;19(16):4362-71
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory