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Rhcg
Gene Detail
 Symbol
Name
ID
Rhcg
Rhesus blood group-associated C glycoprotein
MGI:1888517
Feature Type protein coding gene
Genetic Map
Chromosome 7
45.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:79593363-79617657 bp, - strand
From VEGA annotation of GRCm38

  24295 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32310  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: erythrocyte membrane protein RhD
Gene Tree: Rhcg

Human
homologs
Human Homolog RHCG, Rh family, C glycoprotein
NCBI Gene ID 51458
neXtProt AC  NX_Q9UBD6
Human Synonyms  C15orf6, PDRC2, RHGK, SLC42A3
Human Chr (Location)  15q25; chr15:89471407-89496613 (-)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele have reduced ability to excrete ammonium in their urine and have reduced male fertility.
 
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process ammonium transmembrane transport, ammonium transport, ...
Component apical plasma membrane, basolateral plasma membrane, ...
Function ammonium transmembrane transporter activity, ankyrin binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (11)    Tissues (3)    Images (11)
Theiler Stages: 23
Assay TypeResults
RNA in situ 11
cDNA source data(20)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(22) cDNA(20) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000025008 (Evidence)
Ensembl Gene ModelENSMUSG00000030549 (Evidence)
Entrez Gene56315 (Evidence)
UniGene10909
DFCITC1581472
DoTSDT.101357242, DT.40142550
NIA Mouse Gene IndexU028744
Consensus CDS ProjectCCDS21383.1
International Mouse Knockout Project StatusRhcg
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025008 VEGA Gene Model | MGI Sequence Detail 24295 C57BL/6J ±  kb
transcript OTTMUST00000061558 VEGA | MGI Sequence Detail 2090 Not Applicable 
polypeptide OTTMUSP00000030210 VEGA | MGI Sequence Detail 498 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(4) UniProt(4)
Polymorphisms PCR(1) : SNPs within 2kb(107 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024041 Ammonium transporter AmtB-like domain
InterPro IPR002229 Blood group Rhesus C/E/D polypeptide
Protein Ontology PR:000013974 ammonium transporter Rh type C
References (Earliest) J:63941 Liu Z, et al., Characterization of human RhCG and mouse Rhcg as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis. J Biol Chem. 2000 Aug 18;275(33):25641-51
(Latest) J:206295 Lee HW, et al., Effect of collecting duct-specific deletion of both Rh B Glycoprotein (Rhbg) and Rh C Glycoprotein (Rhcg) on renal response to metabolic acidosis. Am J Physiol Renal Physiol. 2014 Feb;306(4):F389-400
All references(38)
Other
accession IDs
MGI:2142280

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory