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Cxcl14
Gene Detail
Symbol

Name
ID
Cxcl14
chemokine (C-X-C motif) ligand 14
MGI:1888514
Synonyms
1110031L23Rik, 1200006I23Rik, BRAK, Kec, MIP-2g, Scyb14
Feature Type
protein coding gene
Genetic Map
Chromosome 13
30.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:56288647-56296551 bp, - strand
From Ensembl annotation of GRCm38

  7905 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3592  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: CXC chemokine
Gene Tree: Cxcl14

Human
homologs
Human Homolog CXCL14, chemokine (C-X-C motif) ligand 14
NCBI Gene ID 9547
neXtProt AC  NX_O95715
Human Synonyms  BMAC, BRAK, KEC, KS1, MIP-2g, MIP2G, NJAC, SCYB14
Human Chr (Location)  5q31; chr5:135570679-135579279 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
 
Homozygous null mutant cause partial lethality before weaning, however surviving null are small but fertile and show insulin-sensitive phenotype in female under high fat diet feeding condition.
 
Interactions
Cxcl14 interacts with 200 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process immune response, inner ear development, ...
Component extracellular region, extracellular space, ...
Function chemokine activity, cytokine activity
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (147)    Tissues (112)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RNA in situ 133
Northern blot 2
RT-PCR 10
cDNA source data(89)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(93) Genomic(1) cDNA(90) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000021508 (Evidence)
Entrez Gene57266 (Evidence)
UniGene30211
DFCITC1575864, TC1596009
DoTSDT.495199, DT.97413592
NIA Mouse Gene IndexU066052
Consensus CDS ProjectCCDS36679.1
International Mouse Knockout Project StatusCxcl14
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021508 Ensembl Gene Model | MGI Sequence Detail 7905 C57BL/6J ±  kb
transcript ENSMUST00000021970 Ensembl | MGI Sequence Detail 1823 Not Applicable 
polypeptide ENSMUSP00000021970 Ensembl | MGI Sequence Detail 99 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(85 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001811 Chemokine interleukin-8-like domain
Protein Ontology PR:000006068 C-X-C motif chemokine 14
References
(Earliest) J:63970 Cao X, et al., Molecular cloning and characterization of a novel CXC chemokine macrophage inflammatory protein-2 gamma chemoattractant for human neutrophils and dendritic cells. J Immunol. 2000 Sep 1;165(5):2588-95
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(55)
Other
accession IDs
MGI:1915056, MGI:1915961, MGI:2145226

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory