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Gabrq
Gene Detail
Symbol

Name
ID
Gabrq
gamma-aminobutyric acid (GABA) A receptor, subunit theta
MGI:1888498
Feature Type
protein coding gene
Genetic Map
Chromosome X
37.29 cM, cytoband A6
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:72825178-72842602 bp, + strand
From VEGA annotation of GRCm38

  17425 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10233  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: GABRQ
Gene Tree: Gabrq

Human
homologs
GABRQ, gamma-aminobutyric acid (GABA) A receptor, theta
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 55879
neXtProt AC: NX_Q9UN88

Human Synonyms: THETA

Human Chr (Location): Xq28; chrX:152637895-152659510 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
 
Males hemizygous for a mutation in this gene exhibit decreased prepulse inhibition.
 
Interactions
Gabrq interacts with 388 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (86)    Tissues (52)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
In situ reporter (knock in) 48
RT-PCR 38
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000017852 (Evidence)
Ensembl Gene Model ENSMUSG00000031344 (Evidence)
Entrez Gene 57249 (Evidence)
DFCI TC1617403, TC1593486
DoTS DT.101715019, DT.99852916
NIA Mouse Gene Index U019927
Consensus CDS Project CCDS30188.1, CCDS72390.1
International Mouse Phenotyping Consortium Status Gabrq
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017852 VEGA Gene Model | MGI Sequence Detail 17425 C57BL/6J ±  kb
transcript OTTMUST00000043205 VEGA | MGI Sequence Detail 2000 Not Applicable 
polypeptide OTTMUSP00000019435 VEGA | MGI Sequence Detail 638 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(67 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006028 Gamma-aminobutyric acid A receptor
InterPro IPR008101 Gamma-aminobutyric-acid A receptor theta subunit
InterPro IPR006201 Neurotransmitter-gated ion-channel
InterPro IPR018000 Neurotransmitter-gated ion-channel, conserved site
InterPro IPR006202 Neurotransmitter-gated ion-channel ligand-binding
InterPro IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Protein Ontology PR:000007781 gamma-aminobutyric acid receptor subunit theta
References
(Earliest) J:62100 Sinkkonen ST, et al., GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus. J Neurosci. 2000 May 15;20(10):3588-95
(Latest) J:194542 Ghai R, et al., Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E643-52
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory