Mast1
Gene Detail

Symbol Name ID

Mast1 microtubule associated serine/threonine kinase 1 MGI:1861901

Synonyms

9430008B02Rik, SAST, SAST170

Feature Type

protein coding gene

Genetic Map

Chromosome 8

41.32 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr8:84911903-84937359 bp, - strand From VEGA annotation of GRCm38   25457 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10543  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Gene Tree: Mast1

Human homologs

Human Homolog		MAST1, microtubule associated serine/threonine kinase 1
NCBI Gene ID		22983
neXtProt AC		NX_Q9Y2H9
Human Synonyms		SAST, SAST170
Human Chr (Location)		19p13.2; chr19:12949259-12985766 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(8) : Targeted(2) Gene trapped(6)

Gene Ontology (GO) classifications

All GO classifications: (20 annotations)

Process	cytoskeleton organization, phosphorylation, ...
Component	cytoplasm, cytoskeleton, ...
Function	ATP binding, kinase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (16)    Tissues (10)    Images (12)
Theiler Stages: 22, 24, 26, 28

Assay Type	Results
RNA in situ	16

cDNA source data(74)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(78) cDNA(78)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000029992 (Evidence)
Ensembl Gene Model	ENSMUSG00000053693 (Evidence)
Entrez Gene	56527 (Evidence)
UniGene	154614
DFCI	TC1580821, TC1596272, TC1606626, TC1627500
NIA Mouse Gene Index	U030043
EC	2.7.11.1
Consensus CDS Project	CCDS40415.1
International Mouse Knockout Project Status	Mast1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000029992	VEGA Gene Model | MGI Sequence Detail	25457	C57BL/6J
transcript	OTTMUST00000074382	VEGA | MGI Sequence Detail	4872	Not Applicable
polypeptide	OTTMUSP00000038699	VEGA | MGI Sequence Detail	1570	Not Applicable

All sequences(39) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(68 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000961	AGC-kinase, C-terminal
InterPro	IPR015022	Microtubule-associated serine/threonine-protein kinase, domain
InterPro	IPR023142	Microtubule-associated serine/threonine-protein kinase, pre-PK domain
InterPro	IPR001478	PDZ domain
InterPro	IPR000719	Protein kinase, catalytic domain
InterPro	IPR011009	Protein kinase-like domain
InterPro	IPR002290	Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro	IPR008271	Serine/threonine-protein kinase, active site
Protein Ontology	PR:000010195	microtubule-associated serine/threonine-protein kinase 1

References

(Earliest) J:63891 Lumeng C, et al., Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases. Nat Neurosci. 1999 Jul;2(7):611-7
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)

Other accession IDs

MGI:1924506