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Mast1 Gene Detail
Summary
  • Symbol
    Mast1
  • Name
    microtubule associated serine/threonine kinase 1
  • Synonyms
    9430008B02Rik, SAST, SAST170
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861901
    NCBI Gene: 56527
  • Gene Overview
    MyGene.info: MAST1
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr8:84911903-84937359 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      25457 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 41.32 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MAST1, microtubule associated serine/threonine kinase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MAST1, microtubule associated serine/threonine kinase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SAST
  • Links
    NCBI Gene ID: 22983
    neXtProt AC: NX_Q9Y2H9
    UniProt: Q9Y2H9

  • Chr Location
    19p13.13; chr19:12833931-12874953 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    31 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029992 VEGA Gene Model | MGI Sequence Detail 25457 C57BL/6J ±  kb
transcript OTTMUST00000074382 VEGA | MGI Sequence Detail 4872 Not Applicable  
polypeptide OTTMUSP00000038699 VEGA | MGI Sequence Detail 1570 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    201 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000010195 microtubule-associated serine/threonine-protein kinase 1
  • EC
  • InterPro Domains
    IPR000961 AGC-kinase, C-terminal
    IPR028777 Microtubule-associated serine/threonine-protein kinase 1
    IPR015022 Microtubule-associated serine/threonine-protein kinase, domain
    IPR023142 Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily
    IPR001478 PDZ domain
    IPR036034 PDZ superfamily
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain superfamily
    IPR008271 Serine/threonine-protein kinase, active site
Molecular
Reagents
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  • All nucleic 78
    cDNA 78

    Microarray probesets 4
Other
Accession IDs
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MGI:1924506
References
more
  • Summaries
    All 56
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 31
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
  • Latest
    J:221960 Raike RS, et al., Dystonia and cerebellar degeneration in the leaner mouse mutant. Brain Res. 2015 Jun 22;1611:56-64

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory