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Rbms1 Gene Detail
Summary
  • Symbol
    Rbms1
  • Name
    RNA binding motif, single stranded interacting protein 1
  • Synonyms
    2600014B10Rik, MSSP-1, MSSP-2, MSSP-3, YC1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861774
    NCBI Gene: 56878
  • Gene Overview
    MyGene.info: RBMS1
Location & Maps
more
  • Sequence Map
    Chr2:60750193-60963192 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      213000 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 34.95 cM, cytoband C3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RBMS1, RNA binding motif single stranded interacting protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RBMS1, RNA binding motif single stranded interacting protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C2orf12, HCC-4, MSSP, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1
  • Links
    NCBI Gene ID: 5937
    neXtProt AC: NX_P29558

  • Chr Location
    2q24.2; chr2:160272151-160493856 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    47
  • Chemically induced (other)
    1
  • Gene trapped
    39
  • Targeted
    7
  • Genomic Mutations
    1 involving Rbms1
  • Incidental Mutations
Only about half the expected number of mice homozygous for disruptions in this gene are produced in matings of heterozygotes. Embryo sizes are reduced. Females have smaller than normal uteri and decreased levels of progesterone during estrus.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016821 VEGA Gene Model | MGI Sequence Detail 213000 C57BL/6J ±  kb
transcript OTTMUST00000030807 VEGA | MGI Sequence Detail 4436 Not Applicable  
polypeptide OTTMUSP00000013802 VEGA | MGI Sequence Detail 403 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1141 from dbSNP Build 142
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000013811 RNA-binding motif, single-stranded-interacting protein 1
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR002343 Paraneoplastic encephalomyelitis antigen
    IPR000504 RNA recognition motif domain
Molecular
Reagents
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  • All nucleic 23
    cDNA 22
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
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MGI:1919705, MGI:2138868
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 15
  • Earliest
    J:59635 Fujimoto M, et al., Structures and comparison of genomic and complementary DNAs of mouse MSSP, a c-Myc binding protein. Int J Oncol. 2000 Feb;16(2):245-51
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory