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Rbms1
Gene Detail
 Symbol
Name
ID
Rbms1
RNA binding motif, single stranded interacting protein 1
MGI:1861774
Synonyms 2600014B10Rik, MSSP-1, MSSP-2, MSSP-3, YC1
Feature Type protein coding gene
Genetic Map
Chromosome 2
34.95 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:60750193-60963192 bp, - strand
From VEGA annotation of GRCm38

  213000 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9640  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: RNA-binding motif, single-stranded-interacting protein
Gene Tree: Rbms1

Human
homologs
Human Homolog RBMS1, RNA binding motif, single stranded interacting protein 1
NCBI Gene ID 5937
neXtProt AC  NX_P29558
Human Synonyms  C2orf12, HCC-4, MSSP, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1
Human Chr (Location)  2q24.2; chr2:160272151-160493855 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(45) : Gene trapped(39) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Only about half the expected number of mice homozygous for disruptions in this gene are produced in matings of heterozygotes. Embryo sizes are reduced. Females have smaller than normal uteri and decreased levels of progesterone during estrus.
 
Interactions
Rbms1 interacts with 376 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process DNA replication
Component nucleus
Function DNA binding, nucleic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (63)    Tissues (49)    Images (16)
Theiler Stages: 19, 21, 23, 27, 28
Assay TypeResults
RNA in situ 61
RT-PCR 2
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(22) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000016821 (Evidence)
Ensembl Gene ModelENSMUSG00000026970 (Evidence)
Entrez Gene56878 (Evidence)
DFCITC1578604, TC1586993, TC1609565, TC1619880, TC1633813, TC1698128
DoTSDT.101170951, DT.110716482, DT.490403, DT.91551371, DT.94216660, DT.94216677
NIA Mouse Gene IndexU022672, U267579
Consensus CDS ProjectCCDS50590.1, CCDS50591.1
International Mouse Knockout Project StatusRbms1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016821 VEGA Gene Model | MGI Sequence Detail 213000 C57BL/6J ±  kb
transcript OTTMUST00000030807 VEGA | MGI Sequence Detail 4436 Not Applicable 
polypeptide OTTMUSP00000013802 VEGA | MGI Sequence Detail 403 Not Applicable 

For the selected sequences
All sequences(90) RefSeq(12) UniProt(8)
Polymorphisms SNPs within 2kb(1143 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR002343 Paraneoplastic encephalomyelitis antigen
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000013811 RNA-binding motif, single-stranded-interacting protein 1
References (Earliest) J:59635 Fujimoto M, et al., Structures and comparison of genomic and complementary DNAs of mouse MSSP, a c-Myc binding protein. Int J Oncol. 2000 Feb;16(2):245-51
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(42)
Other
accession IDs
MGI:1919705, MGI:2138868

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory