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Nsmf Gene Detail
Summary
  • Symbol
    Nsmf
  • Name
    NMDA receptor synaptonuclear signaling and neuronal migration factor
  • Synonyms
    Jacob, Nelf
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861755
    NCBI Gene: 56876
Location & Maps
more
  • Sequence Map
    Chr2:25054355-25062881 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8527 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    NSMF, NMDA receptor synaptonuclear signaling and neuronal migration factor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NSMF, NMDA receptor synaptonuclear signaling and neuronal migration factor
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HH9, NELF
  • Links
    NCBI Gene ID: 26012
    neXtProt AC: NX_Q6X4W1

  • Chr Location
    9q34.3; chr9:137447570-137459357 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human NSMF associations

Human Disease Mouse Models
       Hypogonadotropic Hypogonadism 9 with or without Anosmia; HH9   OMIM: 614838
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    1
  • Targeted
    1
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011615 VEGA Gene Model | MGI Sequence Detail 8527 C57BL/6J ±  kb
transcript OTTMUST00000027151 VEGA | MGI Sequence Detail 2957 Not Applicable  
polypeptide OTTMUSP00000012357 VEGA | MGI Sequence Detail 532 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    44 from dbSNP Build 137
Protein
Information
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  • UniProt
    12 Sequences
  • Protein Ontology
    PR:000011136 nasal embryonic luteinizing hormone-releasing hormone factor
  • InterPro Domains
    IPR000048 IQ motif, EF-hand binding site
    IPR027401 Myosin-like IQ motif-containing domain
Molecular
Reagents
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  • All nucleic 85
    cDNA 84
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:63404 Kramer PR, et al., Novel gene expressed in nasal region influences outgrowth of olfactory axons and migration of luteinizing hormone-releasing hormone (LHRH) neurons. Genes Dev. 2000 Jul 15;14(14):1824-34
  • Latest
    J:204492 Patel MC, et al., BRD4 coordinates recruitment of pause release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon-stimulated genes. Mol Cell Biol. 2013 Jun;33(12):2497-507

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory