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Gabarap Gene Detail
Summary
  • Symbol
    Gabarap
  • Name
    gamma-aminobutyric acid receptor associated protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861742
    NCBI Gene: 56486
  • Gene Overview
    MyGene.info: GABARAP
Location & Maps
more
  • Sequence Map
    Chr11:69991143-69994951 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3809 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 42.95 cM, cytoband B4
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GABARAP, GABA type A receptor-associated protein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    GABARAP, GABA type A receptor-associated protein
    Orthology source: HomoloGene
  • Synonyms
    ATG8A, GABARAP-a, MM46
  • Links
    NCBI Gene ID: 11337
    neXtProt AC: NX_O95166

  • Chr Location
    17p13.1; chr17:7240419-7242434 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    17 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Gene trapped
    8
  • Targeted
    5
  • Genomic Mutations
    2 involving Gabarap
Mice homozygous for a disruption in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006020 VEGA Gene Model | MGI Sequence Detail 3809 C57BL/6J ±  kb
transcript OTTMUST00000013495 VEGA | MGI Sequence Detail 1351 Not Applicable  
polypeptide OTTMUSP00000006254 VEGA | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    36 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000007757 gamma-aminobutyric acid receptor-associated protein
  • InterPro Domains
    IPR004241 Autophagy protein Atg8 ubiquitin-like
    IPR029071 Ubiquitin-related domain
Molecular
Reagents
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  • All nucleic 241
    cDNA 241

    Microarray probesets 3
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 10
    Phenotypes 17
  • Earliest
    J:63409 Kneussel M, et al., The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8594-9
  • Latest
    J:203423 Pampliega O, et al., Functional interaction between autophagy and ciliogenesis. Nature. 2013 Oct 10;502(7470):194-200

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory