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Gabarap Gene Detail
Summary
  • Symbol
    Gabarap
  • Name
    gamma-aminobutyric acid receptor associated protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861742
    NCBI Gene: 56486
  • Gene Overview
    MyGene.info: GABARAP
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr11:69991143-69994951 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      3809 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.95 cM, cytoband B4
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GABARAP, GABA type A receptor-associated protein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    GABARAP, GABA type A receptor-associated protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATG8A, GABARAP-a, MM46
  • Links
    NCBI Gene ID: 11337
    neXtProt AC: NX_O95166
    UniProt: O95166

  • Chr Location
    17p13.1; chr17:7240419-7242434 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Mice homozygous for a disruption in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    5
  • Tissues
    2
  • cDNA Data
    242
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006020 VEGA Gene Model | MGI Sequence Detail 3809 C57BL/6J ±  kb
transcript OTTMUST00000013495 VEGA | MGI Sequence Detail 1351 Not Applicable  
polypeptide OTTMUSP00000006254 VEGA | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    36 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 242
    cDNA 242

    Microarray probesets 3
References
more
  • Summaries
    All 56
    Developmental Gene Expression 2
    Gene Ontology 11
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:258924 Sasai M, et al., Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense. Nat Immunol. 2017 Aug;18(8):899-910
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
07/31/2018
MGI 6.12 		The Jackson Laboratory