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Gabarap
Gene Detail
Symbol

Name
ID
Gabarap
gamma-aminobutyric acid receptor associated protein
MGI:1861742
Feature Type
protein coding gene
Genetic Map
Chromosome 11
42.95 cM, cytoband B4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:69991143-69994951 bp, + strand
From VEGA annotation of GRCm38

  3809 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:134119  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: microtubule-associated proteins 1 light chain 3A/3B
Gene Tree: Gabarap

Human
homologs
Human Homolog GABARAP, GABA(A) receptor-associated protein
NCBI Gene ID 11337
neXtProt AC  NX_O95166
Human Synonyms  ATG8A, GABARAP-a, MM46
Human Chr (Location)  17p13.1; chr17:7240419-7242434 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(8) Targeted(4)
 
Mice homozygous for a disruption in this gene display a normal phenotype.
 
Interactions
Gabarap interacts with 126 markers (Mir1a-1, Mir1a-2, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (38 annotations)
Process apoptotic process, autophagic vacuole assembly, ...
Component actin cytoskeleton, autophagic vacuole, ...
Function beta-tubulin binding, GABA receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(241)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(241) cDNA(241)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000006020 (Evidence)
Ensembl Gene ModelENSMUSG00000018567 (Evidence)
Entrez Gene56486 (Evidence)
UniGene272460
DFCITC1573505
Consensus CDS ProjectCCDS24928.1
International Mouse Knockout Project StatusGabarap
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006020 VEGA Gene Model | MGI Sequence Detail 3809 C57BL/6J ±  kb
transcript OTTMUST00000013495 VEGA | MGI Sequence Detail 1351 Not Applicable 
polypeptide OTTMUSP00000006254 VEGA | MGI Sequence Detail 117 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(36 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004241 Autophagy protein Atg8 ubiquitin-like
Protein Ontology PR:000007757 gamma-aminobutyric acid receptor-associated protein
References
(Earliest) J:63409 Kneussel M, et al., The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8594-9
(Latest) J:203423 Pampliega O, et al., Functional interaction between autophagy and ciliogenesis. Nature. 2013 Oct 10;502(7470):194-200
All references(46)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory