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Cited4 Gene Detail
Summary
  • Symbol
    Cited4
  • Name
    Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
  • Synonyms
    Mrg2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861694
    NCBI Gene: 56222
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:120523769-120525017 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 56.52 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    14 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1861694
 protein coding gene Chr4:120523760-120525017 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028712
 protein coding gene Chr4:121939771-121941019 (+)
A/J MGP_AJ_G0028672
 protein coding gene Chr4:117142256-117143504 (+)
AKR/J MGP_AKRJ_G0028625
 protein coding gene Chr4:119709847-119711095 (+)
BALB/cJ MGP_BALBcJ_G0028695
 protein coding gene Chr4:117750276-117751524 (+)
C3H/HeJ MGP_C3HHeJ_G0028410
 protein coding gene Chr4:121241859-121243107 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029136
 protein coding gene Chr4:126543845-126545093 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026413
 protein coding gene Chr4:111199703-111200948 (+)
CAST/EiJ MGP_CASTEiJ_G0027841
 protein coding gene Chr4:118607232-118608480 (+)
CBA/J MGP_CBAJ_G0028377
 protein coding gene Chr4:129970644-129971892 (+)
DBA/2J MGP_DBA2J_G0028524
 protein coding gene Chr4:117717482-117718730 (+)
FVB/NJ MGP_FVBNJ_G0028490
 protein coding gene Chr4:116240904-116242152 (+)
LP/J MGP_LPJ_G0028624
 protein coding gene Chr4:122072263-122073511 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028518
 protein coding gene Chr4:134804213-134805461 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029173
 protein coding gene Chr4:120778841-120780089 (+)
PWK/PhJ MGP_PWKPhJ_G0027564
 protein coding gene Chr4:114660593-114661841 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027390
 protein coding gene Chr4:117216289-117217539 (+)
WSB/EiJ MGP_WSBEiJ_G0027921
 protein coding gene Chr4:120796637-120797885 (+)



Homology
more
  • Human Ortholog
    CITED4, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CITED4, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
  • Links
    NCBI Gene ID: 163732
    neXtProt AC: NX_Q96RK1
    UniProt: Q96RK1

  • Chr Location
    1p34.2; chr1:40861054-40862363 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    7
  • Genomic Mutations
    4 involving Cited4
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    880
  • Tissues
    126
  • cDNA Data
    52
  • Literature Summary
    15
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070803 Ensembl Gene Model | MGI Sequence Detail 1249 C57BL/6J ±  kb
transcript ENSMUST00000094814 Ensembl | MGI Sequence Detail 1249 Not Applicable  
polypeptide ENSMUSP00000092408 Ensembl | MGI Sequence Detail 182 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 53
    Primer pair 4

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140450, MGI:2144584
References
more
  • Summaries
    All 59
    Developmental Gene Expression 15
    Gene Ontology 4
    Phenotypes 17
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:344102 Racedo SE, et al., Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals. Dev Biol. 2024 Feb;506:72-84
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory