Aldh9a1
Gene Detail

Symbol Name ID

Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 MGI:1861622

Synonyms

ESTM40, TMABA-DH

Feature Type

protein coding gene

Genetic Map

Chromosome 1

74.74 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr1:167349991-167368530 bp, + strand From NCBI annotation of GRCm38   18540 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:55483  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: NAD-dependent aldehyde dehydrogenase
Gene Tree: Aldh9a1

Human homologs

Human Homolog		ALDH9A1, aldehyde dehydrogenase 9 family, member A1
NCBI Gene ID		223
neXtProt AC		NX_P49189
Human Synonyms		ALDH4, ALDH7, ALDH9, E3, TMABADH
Human Chr (Location)		1q23.1; chr1:165631449-165667900 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (24 annotations)

Process	carnitine metabolic process, cellular aldehyde metabolic process, ...
Component	cytoplasm, cytosol, ...
Function	4-trimethylammoniobutyraldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (10)
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(17) cDNA(15) Primer pair(2)
Microarray probesets(5)

Other database links

Ensembl Gene Model	ENSMUSG00000026687 (Evidence)
Entrez Gene	56752 (Evidence)
DFCI	TC1572145, TC1729406, TC1745711
DoTS	DT.101400547, DT.535923
NIA Mouse Gene Index	U001056
EC	1.2.1.3, 1.2.1.47
Consensus CDS Project	CCDS35765.1
International Mouse Knockout Project Status	Aldh9a1

Sequences

Length	Strain/Species
genomic	56752	NCBI Gene Model | MGI Sequence Detail	18540	C57BL/6J
transcript	NM_019993	RefSeq | MGI Sequence Detail	2834	C57BL/6
polypeptide	Q9JLJ2	UniProt | EBI | MGI Sequence Detail	494	Not Applicable

All sequences(57) RefSeq(2) UniProt(9)

Polymorphisms

SNPs(88 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR016160	Aldehyde dehydrogenase, conserved site
InterPro	IPR016163	Aldehyde dehydrogenase, C-terminal
InterPro	IPR015590	Aldehyde dehydrogenase domain
InterPro	IPR016162	Aldehyde dehydrogenase, N-terminal
InterPro	IPR016161	Aldehyde/histidinol dehydrogenase
Protein Ontology	PR:000003933	4-trimethylaminobutyraldehyde dehydrogenase

Graphical View of Protein Domain Structure

References

(Earliest) J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Other accession IDs

MGI:1334434