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Gbf1 Gene Detail
Summary
  • Symbol
    Gbf1
  • Name
    golgi-specific brefeldin A-resistance factor 1
  • Synonyms
    1700083E03Rik, mKIAA0248
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861607
    NCBI Gene: 107338
  • Gene Overview
    MyGene.info: GBF1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:46152509-46286510 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 38.75 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    495 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1861607
protein coding gene Chr19:46152509-46286510 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025202
protein coding gene Chr19:45824469-45967573 (+)
A/J MGP_AJ_G0025178
protein coding gene Chr19:43569710-43703241 (+)
AKR/J MGP_AKRJ_G0025147
protein coding gene Chr19:44974763-45120040 (+)
BALB/cJ MGP_BALBcJ_G0025173
protein coding gene Chr19:43624948-43762319 (+)
C3H/HeJ MGP_C3HHeJ_G0024933
protein coding gene Chr19:45148630-45286974 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025616
protein coding gene Chr19:46958761-47114280 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023030
protein coding gene Chr19:42808333-42937942 (+)
CAST/EiJ MGP_CASTEiJ_G0024398
protein coding gene Chr19:44931898-45076969 (+)
CBA/J MGP_CBAJ_G0024913
protein coding gene Chr19:49327474-49469529 (+)
DBA/2J MGP_DBA2J_G0025045
protein coding gene Chr19:43387856-43526275 (+)
FVB/NJ MGP_FVBNJ_G0025006
protein coding gene Chr19:43164818-43303731 (+)
LP/J MGP_LPJ_G0025131
protein coding gene Chr19:45736992-45875270 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025037
protein coding gene Chr19:48675706-48816857 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025674
protein coding gene Chr19:45085871-45228097 (+)
PWK/PhJ MGP_PWKPhJ_G0024147
protein coding gene Chr19:43324944-43464298 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023951
protein coding gene Chr19:43744264-43877882 (+)
WSB/EiJ MGP_WSBEiJ_G0024468
protein coding gene Chr19:45229191-45367314 (+)



Homology
more
  • Human Ortholog
    GBF1, golgi brefeldin A resistant guanine nucleotide exchange factor 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GBF1, golgi brefeldin A resistant guanine nucleotide exchange factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARF1GEF
  • Links
    NCBI Gene ID: 8729
    neXtProt AC: NX_Q92538
    UniProt: Q92538

  • Chr Location
    10q24.32; chr10:102245498-102382899 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 107338 NCBI Gene Model | MGI Sequence Detail 134002 C57BL/6J ±  kb
    transcript NM_178930 RefSeq | MGI Sequence Detail 6422 C57BL/6  
    polypeptide NP_849261 RefSeq | MGI Sequence Detail 1861 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 225
      cDNA 223
      Primer pair 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1920768, MGI:2147472, MGI:2147694
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:63167 Semina EV, et al., Deletion in the promoter region and altered expression of pitx3 homeobox gene in aphakia mice. Hum Mol Genet. 2000 Jul 1;9(11):1575-85
    • Latest
      J:209956 Liakath-Ali K, et al., Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. Nat Commun. 2014;5:3540

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory