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Cpsf4 Gene Detail
Summary
  • Symbol
    Cpsf4
  • Name
    cleavage and polyadenylation specific factor 4
  • Synonyms
    30kDa
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861602
    NCBI Gene: 54188
  • Gene Overview
    MyGene.info: CPSF4
Location & Maps
more
  • Sequence Map
    Chr5:145167213-145182041 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14829 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CPSF4, cleavage and polyadenylation specific factor 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CPSF4, cleavage and polyadenylation specific factor 4
    Orthology source: HomoloGene
  • Synonyms
    CPSF30, NAR, NEB1, NEB-1
  • Links
    NCBI Gene ID: 10898
    neXtProt AC: NX_O95639

  • Chr Location
    7q22.1; chr7:99438940-99457373 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 38216
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CPSF4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    12
  • Gene trapped
    10
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023017 VEGA Gene Model | MGI Sequence Detail 14829 C57BL/6J ±  kb
transcript OTTMUST00000055568 VEGA | MGI Sequence Detail 1756 Not Applicable  
polypeptide OTTMUSP00000026622 VEGA | MGI Sequence Detail 269 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    109 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000005832 cleavage and polyadenylation specificity factor subunit 4
  • InterPro Domains
    IPR000571 Zinc finger, CCCH-type
    IPR001878 Zinc finger, CCHC-type
Molecular
Reagents
less
  • All nucleic 77
    cDNA 76
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141311
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory