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Cpsf2 Gene Detail
Summary
  • Symbol
    Cpsf2
  • Name
    cleavage and polyadenylation specific factor 2
  • Synonyms
    100kDa, 2610024B04Rik, Cpsf, mKIAA1367
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861601
    NCBI Gene: 51786
  • Gene Overview
    MyGene.info: CPSF2
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr12:101975764-102005993 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30230 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 51.34 cM, cytoband F1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CPSF2, cleavage and polyadenylation specific factor 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CPSF2, cleavage and polyadenylation specific factor 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CPSF100
  • Links
    NCBI Gene ID: 53981
    neXtProt AC: NX_Q9P2I0
    UniProt: Q9P2I0

  • Chr Location
    14q32.12; chr14:92121954-92164199 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 51786 NCBI Gene Model | MGI Sequence Detail 30230 C57BL/6J ±  kb
transcript NM_016856 RefSeq | MGI Sequence Detail 5315 C57BL/6  
polypeptide O35218 UniProt | EBI | MGI Sequence Detail 782 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    314 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000005829 cleavage and polyadenylation specificity factor subunit 2
  • InterPro Domains
    IPR022712 Beta-Casp domain
    IPR025069 Cleavage and polyadenylation specificity factor 2, C-terminal
    IPR027075 Cleavage and polyadenylation specificity factor subunit 2
    IPR035639 CPSF2, metallo-hydrolase domain
    IPR001279 Metallo-beta-lactamase
    IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
    IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 6
Other
Accession IDs
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MGI:1917185, MGI:2144878
References
more
  • Summaries
    All 41
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory