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Krt71
Gene Detail
Symbol

Name
ID
Krt71
keratin 71
MGI:1861586
Synonyms
Ca, Cal4, Cu, Krt2-6g, mK6irs, mK6irs1
Feature Type
protein coding gene
Genetic Map
Chromosome 15
57.00 cM
Detailed Genetic Map ± 1 cM


Mapping data(49)
Sequence Map
Chr15:101733950-101743109 bp, - strand
From VEGA annotation of GRCm38

  9160 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:88864  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken

Gene Tree: Krt71

Human
homologs
Human Homolog KRT71, keratin 71
NCBI Gene ID 112802
neXtProt AC  NX_Q3SY84
Human Synonyms  HYPT13, K6IRS1, KRT6IRS, KRT6IRS1
Human Chr (Location)  12q13.13; chr12:52543909-52553147 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human KRT71
Mutations,
alleles, and
phenotypes
All mutations/alleles(28) : Chemically induced (ENU)(5) Radiation induced(2) Spontaneous(16) Targeted(5)
Genomic Mutations involving Krt71 (2)
Incidental mutations (data from Mutagenetix , APF )
 
A number of independent spontaneous mutations in this gene result in a similar dominant phenotype, with curved vibrissae and wavy hair. ENU mutants have also been characterized for abnormalities of keratinization in the inner root sheath of the hair follicle, including one recessive allele.
 
Phenotype Images(6)
Interactions
Krt71 interacts with 87 markers (Mir1b, Mir23b, Mir24-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (21)    Tissues (3)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 3
RNA in situ 18
cDNA source data(134)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(137) Genomic(1) cDNA(136)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027989 (Evidence)
Ensembl Gene ModelENSMUSG00000051879 (Evidence)
Entrez Gene56735 (Evidence)
UniGene358677
DFCITC1576719
DoTSDT.110836419, DT.60111722
NIA Mouse Gene IndexU162506
Consensus CDS ProjectCCDS27862.1
International Mouse Knockout Project StatusKrt71
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027989 VEGA Gene Model | MGI Sequence Detail 9160 C57BL/6J ±  kb
transcript OTTMUST00000069333 VEGA | MGI Sequence Detail 2185 Not Applicable 
polypeptide OTTMUSP00000035196 VEGA | MGI Sequence Detail 524 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(70 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001664 Intermediate filament protein
InterPro IPR018039 Intermediate filament protein, conserved site
InterPro IPR003054 Type II keratin
Protein Ontology PR:000009486 keratin, type II cytoskeletal 71
References
(Earliest) J:13054 Dunn LC, Caracul, a dominant mutation. J Hered. 1937;28:334
(Latest) J:193107 Jin C, et al., Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis. Dev Biol. 2013 Feb 1;374(1):96-107
All references(88)
Other
accession IDs
MGD-MRK-1716, MGD-MRK-2251, MGI:2145920, MGI:3044778, MGI:88238

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory