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Krt71
Gene Detail
Symbol

Name
ID
Krt71
keratin 71
MGI:1861586
Synonyms
Ca, Cal4, Cu, Krt2-6g, mK6irs, mK6irs1
Feature Type
protein coding gene
Genetic Map
Chromosome 15
57.00 cM
Detailed Genetic Map ± 1 cM


Mapping data(49)
Sequence Map
Chr15:101733950-101743109 bp, - strand
From VEGA annotation of GRCm38

  9160 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:88864  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken

HCOP human homology predictions: KRT71
Gene Tree: Krt71

Human
homologs
KRT71, keratin 71, type II
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 112802
neXtProt AC: NX_Q3SY84

Human Synonyms: HYPT13, K6IRS1, KRT6IRS, KRT6IRS1

Human Chr (Location): 12q13.13; chr12:52543909-52553147 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human KRT71

Mutations,
alleles, and
phenotypes
All mutations/alleles(29) : Chemically induced (ENU)(5) Radiation induced(2) Spontaneous(17) Targeted(5)
Genomic Mutations involving Krt71 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mutations in this gene result in waved hair and curly vibrissae.
 
Human Diseases Modeled in Mice Using Krt71 (1)    Mutations Annotated to Human Diseases (1)    Phenotype Images(8)
Interactions
Krt71 interacts with 87 markers (Mir1b, Mir23b, Mir24-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cytoskeleton organization, hair follicle morphogenesis, ...
Component cytoplasm, cytoskeleton, ...
Function structural constituent of cytoskeleton, structural molecule activity
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (21)    Tissues (3)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 3
RNA in situ 18
cDNA source data(134)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(137) Genomic(1) cDNA(136)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000027989 (Evidence)
Ensembl Gene Model ENSMUSG00000051879 (Evidence)
Entrez Gene 56735 (Evidence)
UniGene 358677
DFCI TC1576719
DoTS DT.60111722, DT.110836419
NIA Mouse Gene Index U162506
Consensus CDS Project CCDS27862.1
International Mouse Phenotyping Consortium Status Krt71
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027989 VEGA Gene Model | MGI Sequence Detail 9160 C57BL/6J ±  kb
transcript OTTMUST00000069333 VEGA | MGI Sequence Detail 2185 Not Applicable 
polypeptide OTTMUSP00000035196 VEGA | MGI Sequence Detail 524 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(70 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001664 Intermediate filament protein
InterPro IPR018039 Intermediate filament protein, conserved site
InterPro IPR003054 Type II keratin
Protein Ontology PR:000009486 keratin, type II cytoskeletal 71
References
(Earliest) J:13054 Dunn LC, Caracul, a dominant mutation. J Hered. 1937;28:334
(Latest) J:222308 Fairfield H, et al., Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. Genome Res. 2015 Jul;25(7):948-57
All references(91)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-1716, MGD-MRK-2251, MGI:2145920, MGI:3044778, MGI:88238

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory