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Trim17 Gene Detail
Summary
  • Symbol
    Trim17
  • Name
    tripartite motif-containing 17
  • Synonyms
    Rnf16, terf
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861440
    NCBI Gene: 56631
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:58954702-58973097 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 36.38 cM, cytoband B1.2-B1.3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    298 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1861440
protein coding gene Chr11:58954685-58973098 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018385
protein coding gene Chr11:58745772-58753538 (+)
A/J MGP_AJ_G0018354
protein coding gene Chr11:56505179-56512999 (+)
AKR/J MGP_AKRJ_G0018324
protein coding gene Chr11:58405696-58413610 (+)
BALB/cJ MGP_BALBcJ_G0018325
protein coding gene Chr11:56874385-56882295 (+)
C3H/HeJ MGP_C3HHeJ_G0018138
protein coding gene Chr11:58292945-58300808 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018777
protein coding gene Chr11:60621919-60629390 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016421
protein coding gene Chr11:53769489-53787495 (+)
CAST/EiJ MGP_CASTEiJ_G0017695
protein coding gene Chr11:58401395-58419774 (+)
CBA/J MGP_CBAJ_G0018112
protein coding gene Chr11:63266387-63274254 (+)
DBA/2J MGP_DBA2J_G0018221
protein coding gene Chr11:56182919-56190852 (+)
FVB/NJ MGP_FVBNJ_G0018212
protein coding gene Chr11:55830849-55838701 (+)
LP/J MGP_LPJ_G0018294
protein coding gene Chr11:59361520-59369224 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018236
protein coding gene Chr11:64421142-64430417 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018817
protein coding gene Chr11:58401540-58421705 (+)
PWK/PhJ MGP_PWKPhJ_G0017466
protein coding gene Chr11:56769522-56777489 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017259
protein coding gene Chr11:58218403-58226550 (+)
WSB/EiJ MGP_WSBEiJ_G0017746
protein coding gene Chr11:58095680-58105128 (+)



Homology
more
  • Human Ortholog
    TRIM17, tripartite motif containing 17
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TRIM17, tripartite motif containing 17
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RBCC, RNF16, terf
  • Links
    NCBI Gene ID: 51127
    neXtProt AC: NX_Q9Y577
    UniProt: Q9Y577

  • Chr Location
    1q42.13; chr1:228407478-228416882 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56631 NCBI Gene Model | MGI Sequence Detail 18396 C57BL/6J ±  kb
transcript NM_031172 RefSeq | MGI Sequence Detail 3026 Not Specified  
polypeptide Q7TPM3 UniProt | EBI | MGI Sequence Detail 477 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
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  • All nucleic 7
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:205630 Magiera MM, et al., Trim17-mediated ubiquitination and degradation of Mcl-1 initiate apoptosis in neurons. Cell Death Differ. 2013 Feb;20(2):281-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory