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Slc15a1
Gene Detail
Symbol

Name
ID
Slc15a1
solute carrier family 15 (oligopeptide transporter), member 1
MGI:1861376
Synonyms
PECT1, PEPT1
Feature Type
protein coding gene
Genetic Map
Chromosome 14
65.26 cM, cytoband E5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:121459621-121505254 bp, - strand
From NCBI annotation of GRCm38

  45634 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38006  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: SLC15A1
Protein SuperFamily: peptide transport protein PEPT1
Gene Tree: Slc15a1

Human
homologs
SLC15A1, solute carrier family 15 (oligopeptide transporter), member 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 6564
neXtProt AC: NX_P46059

Human Synonyms: HPECT1, HPEPT1, PEPT1

Human Chr (Location): 13q32.3; chr13:98683801-98752675 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(11) Targeted(4)
Incidental mutations (data from APF )
 
Peptide uptake in the intestine is substantially reduced in mice homozygous for a null mutation of this gene.
 
Interactions
Slc15a1 interacts with 151 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc15a1 ; ZFIN slc15a1b    NEW 
Molecular
reagents
All nucleic(8) Genomic(1) cDNA(7)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000025557 (Evidence)
Entrez Gene 56643 (Evidence)
UniGene 155618
DFCI TC1587533
DoTS DT.101202177
NIA Mouse Gene Index U035941
Consensus CDS Project CCDS37017.1
International Mouse Phenotyping Consortium Status Slc15a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 56643 NCBI Gene Model | MGI Sequence Detail 45634 C57BL/6J ±  kb
transcript NM_053079 RefSeq | MGI Sequence Detail 3123 C57BL/6 
polypeptide Q9JIP7 UniProt | EBI | MGI Sequence Detail 709 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(701 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR004768 Oligopeptide transporter
InterPro IPR000109 Proton-dependent oligopeptide transporter family
InterPro IPR018456 PTR2 family proton/oligopeptide symporter, conserved site
Protein Ontology PR:000014940 solute carrier family 15 member 1
Graphical View of Protein Domain Structure
References
(Earliest) J:62996 Fei Y, et al., cDNA structure, genomic organization, and promoter analysis of the mouse intestinal peptide transporter PEPT1. Biochim Biophys Acta. 2000 Jun 21;1492(1):145-54
(Latest) J:210445 Nakamura N, et al., Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. Nature. 2014 May 8;509(7499):240-4
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory