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Chdh
Gene Detail
 Symbol
Name
ID
Chdh
choline dehydrogenase
MGI:1860776
Synonyms D630034H06Rik, MGC:30702
Feature Type protein coding gene
Genetic Map
Chromosome 14
18.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:30009023-30040466 bp, + strand
From VEGA annotation of GRCm38

  31444 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41261  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: glucose-methanol-choline oxidoreductase
Gene Tree: Chdh

Human
homologs
Human Homolog CHDH, choline dehydrogenase
NCBI Gene ID 55349
neXtProt AC  NX_Q8NE62
Human Chr (Location)  3p21.1; chr3:53816297-53846393 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous male mutants show reduced fertility due to reduced sperm motility caused by abnormal mitochondrial function and structures.
 
Interactions
Chdh interacts with 343 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process alcohol metabolic process, glycine betaine biosynthetic process from choline, ...
Component membrane, mitochondrial inner membrane, ...
Function choline dehydrogenase activity, flavin adenine dinucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (126)    Tissues (100)    Images (30)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 126
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) Genomic(1) cDNA(8)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000027809 (Evidence)
Ensembl Gene ModelENSMUSG00000015970 (Evidence)
Entrez Gene218865 (Evidence)
NIA Mouse Gene IndexU015435
EC1.1.99.1
Consensus CDS ProjectCCDS26892.1
International Mouse Knockout Project StatusChdh
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027809 VEGA Gene Model | MGI Sequence Detail 31444 C57BL/6J ±  kb
transcript OTTMUST00000068821 VEGA | MGI Sequence Detail 5629 Not Applicable 
polypeptide OTTMUSP00000034869 VEGA | MGI Sequence Detail 596 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(7) UniProt(3)
Polymorphisms SNPs within 2kb(296 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011533 Choline dehydrogenase
InterPro IPR012132 Glucose-methanol-choline oxidoreductase
InterPro IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal
InterPro IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal
Protein Ontology PR:000005416 choline dehydrogenase, mitochondrial
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)
Other
accession IDs
MGI:2145756

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory