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Eif3i Gene Detail
Summary
  • Symbol
    Eif3i
  • Name
    eukaryotic translation initiation factor 3, subunit I
  • Synonyms
    36kDa, D4Ertd632e, Eif3s2, TRIP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860763
    NCBI Gene: 54709
  • Gene Overview
    MyGene.info: EIF3I
Location & Maps
more
  • Sequence Map
    Chr4:129591960-129600648 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8689 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 63.26 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    EIF3I, eukaryotic translation initiation factor 3 subunit I
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EIF3I, eukaryotic translation initiation factor 3 subunit I
    Orthology source: HGNC, HomoloGene
  • Synonyms
    eIF3-beta, eIF3-p36, EIF3S2, PRO2242, TRIP1, TRIP-1
  • Links
    NCBI Gene ID: 8668
    neXtProt AC: NX_Q13347

  • Chr Location
    1p34.1; chr1:32221867-32231604 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    2
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Eif3i
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009520 VEGA Gene Model | MGI Sequence Detail 8689 C57BL/6J ±  kb
transcript OTTMUST00000021778 VEGA | MGI Sequence Detail 1123 Not Applicable  
polypeptide OTTMUSP00000009935 VEGA | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    81 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006981 eukaryotic translation initiation factor 3 subunit I
  • InterPro Domains
    IPR027525 Eukaryotic translation initiation factor 3 subunit I
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
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  • All nucleic 293
    cDNA 292
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
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MGI:1277123
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:204915 Zeng L, et al., The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control. J Biol Chem. 2013 Oct 18;288(42):30087-93

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory