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Akap8l Gene Detail
Summary
  • Symbol
    Akap8l
  • Name
    A kinase anchor protein 8-like
  • Synonyms
    Nakap95
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860606
    NCBI Gene: 54194
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:32540398-32569581 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.50 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    624 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860606
 protein coding gene Chr17:32540398-32569589 (-)
129S1/SvImJ ENSMUSG00200052823
 protein coding gene Chr17:28222333-28251817 (-)
A/J ENSMUSG00195054212
 protein coding gene Chr17:29161885-29191364 (-)
AKR/J ENSMUSG00220048831
 protein coding gene Chr17:28189877-28219356 (-)
BALB/cJ ENSMUSG00180045366
 protein coding gene Chr17:28496425-28525915 (-)
C3H/HeJ ENSMUSG00175047922
 protein coding gene Chr17:28071009-28100484 (-)
C57BL/6NJ ENSMUSG00215052716
 protein coding gene Chr17:28060225-28089725 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021381
 protein coding gene Chr17:28195007-28227854 (-)
CAST/EiJ ENSTCUG00005044862
 protein coding gene Chr17:29075008-29104487 (-)
CBA/J ENSMUSG00210047975
 protein coding gene Chr17:27897906-27927387 (-)
DBA/2J ENSMUSG00185053514
 protein coding gene Chr17:30508352-30537850 (-)
FVB/NJ ENSMUSG00205049963
 protein coding gene Chr17:28393893-28423390 (-)
JF1/MsJ ENSUMUG00000052250
 protein coding gene Chr17:29810049-29839583 (-)
LP/J ENSMUSG00230054312
 protein coding gene Chr17:31620835-31650331 (-)
NOD/ShiLtJ ENSMUSG00190045270
 protein coding gene Chr17:28020189-28049900 (-)
NZO/HlLtJ ENSMUSG00225050059
 protein coding gene Chr17:33657813-33687305 (-)
PWK/PhJ ENSLUMG00010033232
 protein coding gene Chr17:27635380-27664870 (-)
SPRET/EiJ ENSMSPG00010041547
 protein coding gene Chr17:28764732-28794652 (-)
WSB/EiJ ENSIUOG00005044569
 protein coding gene Chr17:28779120-28808809 (-)



Homology
more
  • Human Ortholog
    AKAP8L, A-kinase anchoring protein 8 like
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AKAP8L, A-kinase anchoring protein 8 like
  • Synonyms
    HA95, HAP95, NAKAP, NAKAP95
  • Links
    NCBI Gene ID: 26993
    UniProt: Q9ULX6

  • Chr Location
    19p13.12; chr19:15380050-15419141 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    643
  • Tissues
    29
  • cDNA Data
    9
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000002625 Ensembl Gene Model | MGI Sequence Detail 29184 C57BL/6J ±  kb
    transcript ENSMUST00000050214 Ensembl | MGI Sequence Detail 2102 Not Applicable  
    polypeptide ENSMUSP00000051389 Ensembl | MGI Sequence Detail 641 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 10
      Primer pair 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory