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Fnbp4 Gene Detail
Summary
  • Symbol
    Fnbp4
  • Name
    formin binding protein 4
  • Synonyms
    FBP30
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860513
    NCBI Gene: 55935
  • Gene Overview
    MyGene.info: FNBP4
Location & Maps
more
  • Sequence Map
    Chr2:90745370-90781021 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      35652 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 50.35 cM, cytoband E1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    FNBP4, formin binding protein 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FNBP4, formin binding protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBP30
  • Links
    NCBI Gene ID: 23360
    neXtProt AC: NX_Q8N3X1

  • Chr Location
    11p11.2; chr11:47716517-47767460 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    32
  • Chemically induced (other)
    1
  • Gene trapped
    26
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Fnbp4
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    2
  • Tissues
    2
  • cDNA Data
    11
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014273 VEGA Gene Model | MGI Sequence Detail 35652 C57BL/6J ±  kb
transcript OTTMUST00000033603 VEGA | MGI Sequence Detail 4691 Not Applicable  
polypeptide OTTMUSP00000015063 VEGA | MGI Sequence Detail 1077 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    65 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001202 WW domain
Molecular
Reagents
less
  • All nucleic 13
    cDNA 11
    Other 2

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:38792 Chan DC, et al., Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J. 1996 Mar 1;15(5):1045-54
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory