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Prpf40a Gene Detail
Summary
  • Symbol
    Prpf40a
  • Name
    pre-mRNA processing factor 40A
  • Synonyms
    2810012K09Rik, FBP11, Fnbp3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860512
    NCBI Gene: 56194
  • Gene Overview
    MyGene.info: PRPF40A
Location & Maps
more
  • Sequence Map
    Chr2:53134704-53191284 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      56581 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 30.69 cM, cytoband C1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PRPF40A, pre-mRNA processing factor 40 homolog A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PRPF40A, pre-mRNA processing factor 40 homolog A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBP11, FBP-11, FLAF1, FNBP3, HIP10, HIP-10, HYPA, NY-REN-6, Prp40
  • Links
    NCBI Gene ID: 55660
    neXtProt AC: NX_O75400

  • Chr Location
    2q23.3; chr2:152651593-152717916 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    29
  • Chemically induced (other)
    1
  • Gene trapped
    28
  • Genomic Mutations
    1 involving Prpf40a
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    136
  • Tissues
    122
  • cDNA Data
    15
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012447 VEGA Gene Model | MGI Sequence Detail 56581 C57BL/6J ±  kb
transcript OTTMUST00000029595 VEGA | MGI Sequence Detail 7374 Not Applicable  
polypeptide OTTMUSP00000013317 VEGA | MGI Sequence Detail 953 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    265 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
less
MGI:1922669
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:38792 Chan DC, et al., Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J. 1996 Mar 1;15(5):1045-54
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory