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Abcb10
Gene Detail
Symbol

Name
ID
Abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
MGI:1860508
Synonyms
ABC-me
Feature Type
protein coding gene
Genetic Map
Chromosome 8
72.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:123952459-123983122 bp, - strand
From VEGA annotation of GRCm38

  30664 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6474  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: ABCB10
Protein SuperFamily: ABC-type transport system, bifunctional permease/ATPase, subfamily B
Gene Tree: Abcb10

Human
homologs
ABCB10, ATP-binding cassette, sub-family B (MDR/TAP), member 10
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 23456
neXtProt AC: NX_Q9NRK6

Human Synonyms: EST20237, M-ABC2, MTABC2

Human Chr (Location): 1q42.13; chr1:229516582-229558695 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit embryonic lethality. Mice heterozygous for this allele exhibit increased response to ischemia and reperfusion.
 
Interactions
Abcb10 interacts with 189 markers (Mir7-1, Mir10a, Mir17, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (134)    Tissues (127)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 116
Northern blot 18
cDNA source data(80)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(84) cDNA(83) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000031206 (Evidence)
Ensembl Gene Model ENSMUSG00000031974 (Evidence)
Entrez Gene 56199 (Evidence)
UniGene 274243
DFCI TC1606713, TC1575451, TC1615271
DoTS DT.493367, DT.101324098, DT.91401977, DT.91346547
NIA Mouse Gene Index U030385
Consensus CDS Project CCDS22766.1
International Mouse Phenotyping Consortium Status Abcb10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031206 VEGA Gene Model | MGI Sequence Detail 30664 C57BL/6J ±  kb
transcript OTTMUST00000077306 VEGA | MGI Sequence Detail 4306 Not Applicable 
polypeptide OTTMUSP00000040853 VEGA | MGI Sequence Detail 715 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(616 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR017871 ABC transporter, conserved site
InterPro IPR003439 ABC transporter-like
InterPro IPR011527 ABC transporter, transmembrane domain, type 1
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000003548 ATP-binding cassette sub-family B member 10, mitochondrial
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:198162 Chen C, et al., Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metab. 2013 Mar 5;17(3):343-52
All references(40)
Other
accession IDs
MGI:2142681, MGI:2142839

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory