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Nmu
Gene Detail
Symbol

Name
ID
Nmu
neuromedin U
MGI:1860476
Feature Type
protein coding gene
Genetic Map
Chromosome 5
40.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:76333495-76363788 bp, - strand
From VEGA annotation of GRCm38

  30294 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4863  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NMU
Protein SuperFamily: neuromedin U
Gene Tree: Nmu

Human
homologs
NMU, neuromedin U
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10874
neXtProt AC: NX_P48645

Human Chr (Location): 4q12; chr4:55595229-55636698 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(7) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice are healthy and viable.
 
Interactions
Nmu interacts with 43 markers (Mir7-1, Mir10a, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process eating behavior, gastric acid secretion, ...
Component extracellular region, terminal bouton
Function neuromedin U receptor binding
External Resources: FuncBase
Expression
cDNA source data(6)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000026473 (Evidence)
Ensembl Gene Model ENSMUSG00000029236 (Evidence)
Entrez Gene 56183 (Evidence)
UniGene 154879
DFCI TC1586915
DoTS DT.50315151
NIA Mouse Gene Index U026320
Consensus CDS Project CCDS19362.1
International Mouse Phenotyping Consortium Status Nmu
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026473 VEGA Gene Model | MGI Sequence Detail 30294 C57BL/6J ±  kb
transcript OTTMUST00000065456 VEGA | MGI Sequence Detail 828 Not Applicable 
polypeptide OTTMUSP00000032629 VEGA | MGI Sequence Detail 174 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(224 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018070 Neuromedin U, amidation site
InterPro IPR008200 Neuromedin U, C-terminal
Protein Ontology PR:000011295 neuromedin-U
References
(Earliest) J:66232 Wilsbacher LD, et al., The mouse clock locus: sequence and comparative analysis of 204 Kb from mouse chromosome 5. Genome Res. 2000 Dec;10(12):1928-40
(Latest) J:151893 Novak CM, Neuromedin S and U. Endocrinology. 2009 Jul;150(7):2985-7
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory