About   Help   FAQ
Nmu Gene Detail
Summary
  • Symbol
    Nmu
  • Name
    neuromedin U
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860476
    NCBI Gene: 56183
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr5:76333495-76363788 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30294 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 40.93 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    NMU, neuromedin U
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NMU, neuromedin U
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10874
    neXtProt AC: NX_P48645
    UniProt: P48645

  • Chr Location
    4q12; chr4:55595229-55636698 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice are healthy and viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026473 VEGA Gene Model | MGI Sequence Detail 30294 C57BL/6J ±  kb
transcript OTTMUST00000065456 VEGA | MGI Sequence Detail 828 Not Applicable  
polypeptide OTTMUSP00000032629 VEGA | MGI Sequence Detail 174 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    224 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 45
    Gene Ontology 6
    Phenotypes 20
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:238509 Doi T, et al., Importance of Water Content of the Stratum Corneum in Mouse Models for Contact Hypersensitivity. J Invest Dermatol. 2017 Jan;137(1):151-158

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/05/2017
MGI 6.11
The Jackson Laboratory