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Nmu Gene Detail
Summary
  • Symbol
    Nmu
  • Name
    neuromedin U
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860476
    NCBI Gene: 56183
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:76481342-76511624 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 40.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    980 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860476
 protein coding gene Chr5:76481342-76511635 (-)
129S1/SvImJ ENSMUSG00200000701
 protein coding gene Chr5:72171518-72201808 (-)
A/J ENSMUSG00195010041
 protein coding gene Chr5:71468323-71498653 (-)
AKR/J ENSMUSG00220014873
 protein coding gene Chr5:71581493-71611818 (-)
BALB/cJ ENSMUSG00180023149
 protein coding gene Chr5:71243250-71273550 (-)
C3H/HeJ ENSMUSG00175004212
 protein coding gene Chr5:73287053-73317419 (-)
C57BL/6NJ ENSMUSG00215000441
 protein coding gene Chr5:72057832-72088128 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027316
 protein coding gene Chr5:69238257-69268890 (-)
CAST/EiJ ENSTCUG00005013259
 protein coding gene Chr5:71029142-71060052 (-)
CBA/J ENSMUSG00210000450
 protein coding gene Chr5:72225057-72255413 (-)
DBA/2J ENSMUSG00185016411
 protein coding gene Chr5:74055002-74085371 (-)
FVB/NJ ENSMUSG00205018822
 protein coding gene Chr5:70991342-71021667 (-)
JF1/MsJ ENSUMUG00000004888
 protein coding gene Chr5:78524702-78555223 (-)
LP/J ENSMUSG00230021518
 protein coding gene Chr5:78745512-78775800 (-)
NOD/ShiLtJ ENSMUSG00190007656
 protein coding gene Chr5:71175451-71205800 (-)
NZO/HlLtJ ENSMUSG00225033181
 protein coding gene Chr5:83792484-83822778 (-)
PWK/PhJ ENSLUMG00010007279
 protein coding gene Chr5:71118049-71148719 (-)
SPRET/EiJ ENSMSPG00010008971
 protein coding gene Chr5:73110187-73139379 (-)
WSB/EiJ ENSIUOG00005018064
 protein coding gene Chr5:74004956-74034831 (-)



Homology
more
  • Human Ortholog
    NMU, neuromedin U
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NMU, neuromedin U
  • Links
    NCBI Gene ID: 10874
    UniProt: P48645

  • Chr Location
    4q12; chr4:55595229-55636793 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human NMU associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    33 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice are healthy and viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    70
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    600
  • Tissues
    3
  • cDNA Data
    7
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56183 NCBI Gene Model | MGI Sequence Detail 30283 C57BL/6J ±  kb
    transcript NM_019515 RefSeq | MGI Sequence Detail 828 BALB/c  
    polypeptide Q9QXK8 UniProt | EBI | MGI Sequence Detail 174 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 2
    References
    more
    • Summaries
      All 70
      Developmental Gene Expression 4
      Gene Ontology 9
      Phenotypes 33
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:377967 Roome RB, et al., Ontogeny of the spinal cord dorsal horn. Science. 2026 Jan 8;391(6781):eadx5781
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory