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Olfm1
Gene Detail
Symbol

Name
ID
Olfm1
olfactomedin 1
MGI:1860437
Synonyms
Noelin 1, Noelin 2, Pancortin 1-4
Feature Type
protein coding gene
Genetic Map
Chromosome 2
19.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:28192992-28230736 bp, + strand
From VEGA annotation of GRCm38

  37745 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8612  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: Noelin/Myocilin
Gene Tree: Olfm1

Human
homologs
Human Homolog OLFM1, olfactomedin 1
NCBI Gene ID 10439
neXtProt AC  NX_Q99784
Human Synonyms  AMY, NOE1, NOELIN1, OlfA
Human Chr (Location)  9q34.3; chr9:135075243-135121184 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display decreased cerebral infarction size and reduced fertility.
 
Interactions
Olfm1 interacts with 195 markers (Mir1b, Mir7-1, Mir9-1, ...)
Expression
Literature Summary: (9 records)
Data Summary: Results (431)    Tissues (131)    Images (71)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 415
RT-PCR 16
cDNA source data(12)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(12) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000011625 (Evidence)
Ensembl Gene ModelENSMUSG00000026833 (Evidence)
Entrez Gene56177 (Evidence)
DFCITC1587438, TC1722560, TC1636604, TC1578074, TC1625328, TC1582439
DoTSDT.525612, DT.55189609, DT.50315647, DT.94329431, DT.97331771, DT.97379358
NIA Mouse Gene IndexU001544
Consensus CDS ProjectCCDS15833.1, CCDS15834.1, CCDS15835.1
International Mouse Knockout Project StatusOlfm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011625 VEGA Gene Model | MGI Sequence Detail 37745 C57BL/6J ±  kb
transcript OTTMUST00000027193 VEGA | MGI Sequence Detail 2757 Not Applicable 
polypeptide OTTMUSP00000012372 VEGA | MGI Sequence Detail 485 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(8) UniProt(9)
Polymorphisms
SNPs within 2kb(115 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022082 Neurogenesis glycoprotein
InterPro IPR003112 Olfactomedin-like
InterPro IPR011044 Quinoprotein amine dehydrogenase, beta chain-like
Protein Ontology PR:000011623 noelin
References
(Earliest) J:28008 Harrison SM, et al., Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Development. 1995 Aug;121(8):2479-89
(Latest) J:206619 Nakaya N, et al., Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice. Exp Neurol. 2013 Dec;250:205-18
All references(42)
Other
accession IDs
MGI:2139410

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory