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Olfm1 Gene Detail
Summary
  • Symbol
    Olfm1
  • Name
    olfactomedin 1
  • Synonyms
    Noelin 1, Noelin 2, Pancortin 1-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860437
    NCBI Gene: 56177
  • Gene Overview
    MyGene.info: OLFM1
  • Alliance
  • Transcription Start Sites
    21 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:28193093-28230736 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 19.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    115 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860437
protein coding gene Chr2:28192992-28230736 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025519
protein coding gene Chr2:26213391-26254872 (+)
A/J MGP_AJ_G0025496
protein coding gene Chr2:25244881-25282415 (+)
AKR/J MGP_AKRJ_G0025466
protein coding gene Chr2:26082598-26120147 (+)
BALB/cJ MGP_BALBcJ_G0025492
protein coding gene Chr2:25361269-25400147 (+)
C3H/HeJ MGP_C3HHeJ_G0025253
protein coding gene Chr2:25982401-26020604 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025936
protein coding gene Chr2:27115899-27158288 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023347
protein coding gene Chr2:24051207-24088921 (+)
CAST/EiJ MGP_CASTEiJ_G0024716
protein coding gene Chr2:25894391-25933429 (+)
CBA/J MGP_CBAJ_G0025231
protein coding gene Chr2:28035053-28075172 (+)
DBA/2J MGP_DBA2J_G0025364
protein coding gene Chr2:25052476-25090021 (+)
FVB/NJ MGP_FVBNJ_G0025326
protein coding gene Chr2:24827810-24866558 (+)
LP/J MGP_LPJ_G0025450
protein coding gene Chr2:26174167-26213841 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025357
protein coding gene Chr2:28037811-28076649 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025995
protein coding gene Chr2:25978449-26018133 (+)
PWK/PhJ MGP_PWKPhJ_G0024464
protein coding gene Chr2:24852161-24889964 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024264
protein coding gene Chr2:26142880-26184213 (+)
WSB/EiJ MGP_WSBEiJ_G0024785
protein coding gene Chr2:26119492-26156826 (+)



Homology
more
  • Human Ortholog
    OLFM1, olfactomedin 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    OLFM1, olfactomedin 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AMY, NOE1, NOELIN1, OlfA
  • Links
    NCBI Gene ID: 10439
    neXtProt AC: NX_Q99784
    UniProt: Q99784

  • Chr Location
    9q34.3; chr9:135075243-135121184 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display decreased cerebral infarction size and reduced fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56177 NCBI Gene Model | MGI Sequence Detail 37644 C57BL/6J ±  kb
    transcript NM_019498 RefSeq | MGI Sequence Detail 2727 Not Specified  
    polypeptide O88998 UniProt | EBI | MGI Sequence Detail 485 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 13
      Primer pair 3

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2139410
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 12
      Gene Ontology 7
      Phenotypes 8
    • Earliest
      J:28008 Harrison SM, et al., Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Development. 1995 Aug;121(8):2479-89
    • Latest
      J:226939 Li R, et al., Olfactomedin 1 Deficiency Leads to Defective Olfaction and Impaired Female Fertility. Endocrinology. 2015 Sep;156(9):3344-57

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory