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Olfm1
Gene Detail
Symbol

Name
ID
Olfm1
olfactomedin 1
MGI:1860437
Synonyms
Noelin 1, Noelin 2, Pancortin 1-4
Feature Type
protein coding gene
Genetic Map
Chromosome 2
19.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:28192992-28230736 bp, + strand
From VEGA annotation of GRCm38

  37745 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8612  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: OLFM1
Protein SuperFamily: Noelin/Myocilin
Gene Tree: Olfm1

Human
homologs
OLFM1, olfactomedin 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10439
neXtProt AC: NX_Q99784

Human Synonyms: AMY, NOE1, NOELIN1, OlfA

Human Chr (Location): 9q34.3; chr9:135075243-135121184 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null mutation display decreased cerebral infarction size and reduced fertility.
 
Interactions
Olfm1 interacts with 195 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (9 records)
Data Summary: Results (431)    Tissues (131)    Images (71)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 415
RT-PCR 16
cDNA source data(12)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: GEISHA OLFM1 ; Xenbase olfm1 ; ZFIN olfm1a, olfm1b    NEW 
Molecular
reagents
All nucleic(15) cDNA(12) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000011625 (Evidence)
Ensembl Gene Model ENSMUSG00000026833 (Evidence)
Entrez Gene 56177 (Evidence)
DFCI TC1578074, TC1625328, TC1587438, TC1582439, TC1636604, TC1722560
DoTS DT.97331771, DT.94329431, DT.55189609, DT.525612, DT.50315647, DT.97379358
NIA Mouse Gene Index U001544
PDB 5AMO
Consensus CDS Project CCDS15833.1, CCDS15834.1, CCDS15835.1
International Mouse Phenotyping Consortium Status Olfm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011625 VEGA Gene Model | MGI Sequence Detail 37745 C57BL/6J ±  kb
transcript OTTMUST00000027193 VEGA | MGI Sequence Detail 2757 Not Applicable 
polypeptide OTTMUSP00000012372 VEGA | MGI Sequence Detail 485 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(8) UniProt(5)
Polymorphisms
SNPs within 2kb(115 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022082 Neurogenesis glycoprotein
InterPro IPR003112 Olfactomedin-like
InterPro IPR011044 Quinoprotein amine dehydrogenase, beta chain-like
Protein Ontology PR:000011623 noelin
References
(Earliest) J:28008 Harrison SM, et al., Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Development. 1995 Aug;121(8):2479-89
(Latest) J:217902 Sultana A, et al., Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice. Exp Neurol. 2014 Nov;261:802-11
All references(41)
Other
accession IDs
MGI:2139410

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory